# 2s Disease Surveillance — CDC NNDSS Weekly Data

> 2s Disease Surveillance — CDC NNDSS Weekly Data is a paid API for AI agents from 2s.io, paid per call via x402, $0.0012/call, status unknown (last checked 2026-10-12).

Returns CDC NNDSS weekly disease surveillance counts (current week, cumulative YTD, prior-year comparisons) filterable by disease/condition, US location, and MMWR year.

## Facts

- Endpoint: GET https://2s.io/api/health/disease-surveillance?utm_source=zero.xyz
- Price: $0.0012/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-12
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/2s-disease-surveillance-cdc-nndss-weekly-data-3ac2c203
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_akdSRZE-ZzqXqYr72BCQa

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability 2s-disease-surveillance-cdc-nndss-weekly-data-3ac2c203
```

Example prompt: How many measles cases have been reported in the US so far in 2026? Pull the most recent CDC NNDSS weekly surveillance data for measles among U.S. Residents and show me the cumulative year-to-date count.

## When to prefer this

Use this endpoint when you need authoritative, up-to-date US notifiable disease case counts from the CDC NNDSS — the official federal surveillance system. Prefer it over news or general web searches when ground-truth epidemiological numbers are required. Best for public health monitoring, outbreak detection, research, or compliance reporting where CDC-sourced data is specifically needed.

## Known failure modes

- No matching records returned (total: 0) when the disease substring or location name doesn't match CDC data — check spelling and use supported location strings
- Invalid or out-of-range year parameter (minimum 2022) returns a validation error
- Limit exceeds maximum of 1000 — cap requests accordingly
- Payment failure or insufficient USDC balance returns HTTP 402
- Network timeout if CDC data.cdc.gov upstream is slow

## How this service works

Current US notifiable-disease surveillance from the CDC NNDSS (National Notifiable Diseases Surveillance System) weekly tables. Returns provisional weekly case counts for ~139 nationally notifiable conditions (e.g. Measles, Pertussis, Mumps, Hepatitis A, Lyme disease, Gonorrhea, West Nile, Dengue) by reporting area and MMWR week, updated weekly. Filter by condition (substring, case-insensitive: "measles" matches "Measles, Indigenous"), location (a reporting area: a US state full name like "California", "New York City", "U.S. Residents", a census region like "Pacific", or a territory), year (MMWR year, 2022 to current), and weeks (most-recent N observations). At least one of condition or location is required. Each record reports the current-week count, the previous-52-week maximum, cumulative cases YTD this MMWR year, and cumulative YTD the prior year for same-week comparison. Public-domain CDC federal data via data.cdc.gov. Use this to see live disease activity and outbreaks that postdate an agent's training cutoff.

## Output

A JSON object with an `items` array of weekly surveillance records, each containing the MMWR week and year, reporting location, disease/condition name, current-week case count (with flag if preliminary), cumulative YTD count, prior-year YTD count, and prior 52-week maximum. Also includes total record count, applied filter metadata, and CDC source/license information.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method",
    "queryParams"
   ],
   "properties": {
    "type": {
     "const": "http"
    },
    "method": {
     "const": "GET"
    },
    "queryParams": {
     "required": [],
     "properties": {
      "year": {
       "type": "integer",
       "minimum": 2022,
       "description": "MMWR year, 2022 to current. Omit for most-recent across years."
      },
      "limit": {
       "type": "integer",
       "default": 100,
       "maximum": 1000,
       "minimum": 1
      },
      "weeks": {
       "type": "integer",
       "maximum": 520,
       "minimum": 1,
       "description": "Return roughly the most-recent N weeks of observations."
      },
      "location": {
       "type": "string",
       "description": "Reporting area: state full name (\"California\"), \"New York City\", \"U.S. Residents\", a census region (\"Pacific\"), or a territory."
      },
      "condition": {
       "type": "string",
       "description": "Disease/condition substring, case-insensitive. E.g. \"measles\", \"pertussis\", \"hepatitis\"."
      }
     }
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/2s-disease-surveillance-cdc-nndss-weekly-data-3ac2c203/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from 2s.io](https://www.zero.xyz/host/2s.io/llms.txt)