# ACR/EULAR 2016 Primary Sjögren's Syndrome Classification Score (Shiboski Table 3)

> ACR/EULAR 2016 Primary Sjögren's Syndrome Classification Score (Shiboski Table 3) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-13).

Computes the ACR/EULAR 2016 Sjögren's syndrome classification score from five weighted clinical items and returns whether the patient meets the ≥4 threshold for classification.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/acr_eular_sjogren
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-13
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/acr-eular-2016-primary-sj-gren-s-syndrome-classification-score-a8353584
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_rFJbiq44EEnQ6eCUWurDn

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability acr-eular-2016-primary-sj-gren-s-syndrome-classification-score-a8353584
```

Example prompt: Score this patient under the ACR/EULAR 2016 primary Sjögren's classification: inclusion is met, no exclusions apply, labial biopsy focus score is ≥1, anti-SSA/Ro is positive, ocular staining is positive, Schirmer's test is negative, and UWS is negative — what's the total score and does the patient classify?

## When to prefer this

Use this endpoint when you need to apply the specific ACR/EULAR 2016 (Shiboski Table 3) Sjögren's classification algorithm — not the older 2002 AECG criteria or the 2012 ACR-only criteria. All five clinical test results (biopsy, serology, ocular staining, Schirmer's, UWS) must already be determined by the caller from laboratory and clinical sources; this endpoint only performs the scoring arithmetic and threshold check. Prefer it over manual calculation to avoid arithmetic errors and to ensure the correct item weights (3/3/1/1/1) are applied consistently.

## Known failure modes

- inclusion_met=false: invalid input, request rejected or unscored — caller must ensure at least one AECG dryness criterion or positive ESSDAI domain
- exclusion_present=true: invalid input, request rejected or unscored — caller must confirm absence of all listed exclusions before submitting
- Missing required query parameters: 400-level error if any of the seven required fields are absent
- Boolean type mismatch: passing strings instead of booleans may cause schema validation errors
- Score of 0–3: patient does not classify; this is not an error but agents must not interpret it as a diagnosis of exclusion

## How this service works

ACR/EULAR 2016 primary Sjögren classification (Shiboski Table 3). Required: inclusion_met true (AECG dryness or ESSDAI domain) and exclusion_present false (no radiation, HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-RD). Score: labial biopsy FS ≥1 3, anti-SSA/Ro 3, ocular staining 1, Schirmer 1, UWS 1; max 9; classified iff ≥4. Not a diagnosis. Not AECG 2002. Not 2012 ACR-only. magent does not stain eyes, measure saliva, or read biopsies.

## Output

Returns the numeric total score (0–9) computed from the five weighted items (labial biopsy FS ≥1 = 3 pts, anti-SSA/Ro = 3 pts, ocular staining = 1 pt, Schirmer's = 1 pt, UWS = 1 pt), plus a boolean classification result indicating whether the score is ≥4 (meeting ACR/EULAR 2016 classification threshold). The endpoint does not return a diagnosis; it returns a classification score only.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "inclusion_met",
      "exclusion_present",
      "labial_biopsy_fs_ge_1",
      "anti_ssa_ro",
      "ocular_staining",
      "schirmer",
      "uws"
     ],
     "properties": {
      "uws": {
       "type": "boolean",
       "description": "Unstimulated whole saliva flow rate ≤0.1 ml/minute (Shiboski 2016 Table 3). true scores 1; false scores 0. magent does not measure saliva."
      },
      "schirmer": {
       "type": "boolean",
       "description": "Schirmer's test ≤5 mm/5 minutes in at least one eye (Shiboski 2016 Table 3). true scores 1; false scores 0. magent does not perform Schirmer testing."
      },
      "anti_ssa_ro": {
       "type": "boolean",
       "description": "Anti-SSA/Ro positive as assigned by the caller (Shiboski 2016 Table 3). true scores 3; false scores 0. Anti-SSB/La without SSA is not an item. magent does not assay autoantibodies."
      },
      "inclusion_met": {
       "type": "boolean",
       "description": "Must be true. Shiboski 2016 inclusion as assigned by the caller: at least one AECG ocular or oral dryness question positive, or suspicion of Sjögren's syndrome from ESSDAI with at least one positive domain item. false is invalid and is not scored. magent does not take a dryness history."
      },
      "ocular_staining": {
       "type": "boolean",
       "description": "Ocular staining score ≥5 or van Bijsterveld ≥4 in at least one eye (Shiboski 2016 Table 3). true scores 1; false scores 0. magent does not stain eyes."
      },
      "exclusion_present": {
       "type": "boolean",
       "description": "Must be false. Shiboski 2016 exclusion as assigned by the caller: none of head and neck radiation, active HCV with PCR confirmation, AIDS, sarcoidosis, amyloidosis, graft-versus-host disease, or IgG4-related disease. true is invalid and is not scored. magent does not diagnose exclusion conditions."
      },
      "labial_biopsy_fs_ge_1": {
      
… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/acr-eular-2016-primary-sj-gren-s-syndrome-classification-score-a8353584/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)