# AlphaFold Predicted Protein Structure Lookup

> AlphaFold Predicted Protein Structure Lookup is a paid API for AI agents from saylorinnovations.com, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-01).

Retrieves AlphaFold-predicted 3D protein structure data for a given UniProt accession or gene symbol, including model metadata, pLDDT confidence scores, and download links for PDB/mmCIF/PAE files.

## Facts

- Endpoint: GET https://saylorinnovations.com/api/bio/alphafold/:id?utm_source=zero.xyz
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-01
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/alphafold-predicted-protein-structure-lookup-fb41c204
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_bD_tmFmeIdS7Rc79ro6pw

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability alphafold-predicted-protein-structure-lookup-fb41c204
```

Example prompt: Can you pull the AlphaFold predicted structure for UniProt accession P04637 — I want the pLDDT confidence score, the breakdown of residues by confidence band, and the download links for the PDB and mmCIF files?

## When to prefer this

Use this endpoint when you need programmatic access to AlphaFold structural predictions and confidence metrics for a specific protein, identified by UniProt accession or gene symbol, without needing to interact with the full AlphaFold DB web interface. Prefer this over manual EBI lookups when building automated pipelines that need pLDDT scores, confidence band breakdowns, and structure download links in a single call.

## Known failure modes

- Unknown UniProt accession or gene symbol returns a 404 or empty result
- Gene symbols with multiple mappings may return unexpected isoform structures
- AlphaFold DB upstream unavailability may cause timeout or error
- Proteins with no AlphaFold prediction (e.g. very large or novel proteins) return no data
- Malformed accession format may return a validation error

## How this service works

AlphaFold Predicted Protein Structure. AlphaFold predicted protein structure for a UniProt accession or gene symbol: model id and version, mean pLDDT confidence, fraction of residues per confidence band with an interpretation, and download links (PDB, mmCIF, predicted aligned error). AlphaFold DB (EMBL-EBI / Google DeepMind), CC BY 4.0.

## Output

Returns the AlphaFold model ID and version, the mean pLDDT confidence score (0–100), a breakdown of the fraction of residues in each confidence band (very high, confident, low, very low) with interpretations, and direct download URLs for the predicted structure in PDB format, mmCIF format, and the predicted aligned error (PAE) JSON file.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/alphafold-predicted-protein-structure-lookup-fb41c204/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from saylorinnovations.com](https://www.zero.xyz/host/saylorinnovations.com/llms.txt)