# ASTCT ICANS Consensus Grade Calculator (Adult, Lee 2019)

> ASTCT ICANS Consensus Grade Calculator (Adult, Lee 2019) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).

Computes the adult ASTCT ICANS consensus grade (0–4) from five caller-supplied domain scores: ICE score, level of consciousness, seizure, motor weakness, and ICP/edema.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/astct_icans
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/astct-icans-consensus-grade-calculator-adult-lee-2019-0145a5c9
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_aoxh0x8k_M7cZY0ofIwUd

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability astct-icans-consensus-grade-calculator-adult-lee-2019-0145a5c9
```

Example prompt: Grade the ICANS for a CAR-T patient with an ICE score of 5, level of consciousness awakening to voice, no seizures, no focal motor weakness, and no ICP or edema — give me the ASTCT consensus grade.

## When to prefer this

Use this endpoint when you need a fast, deterministic computation of the adult ASTCT ICANS consensus grade per Lee 2019 Table 6, particularly in CAR-T care workflows, clinical trial pipelines, or agentic monitoring systems. Prefer this over manual look-up tables or generic LLM reasoning when you require reproducible, schema-validated grading that can be audited. Not appropriate for pediatric CAPD grading, CRS scoring, or situations where ICE testing has not already been performed by a clinician.

## Known failure modes

- Missing required query parameter (ice_score, loc, seizure, motor_weakness, or icp) returns a 400/422 error
- ice_score out of range (not 0–10) returns a validation error
- Invalid enum value for loc, seizure, motor_weakness, or icp returns an error
- Network or server errors return 5xx; retry with backoff
- Payment failure (x402) if USDC balance is insufficient

## How this service works

Adult ASTCT ICANS consensus grade (Lee 2019 Table 6). Grade is the most severe of ICE, depressed LOC, seizure, deep focal motor weakness, and ICP/edema. ICE 10 is 0; 7-9 is 1; 3-6 is 2; 0-2 is 3; ICE 0 is 4 if unarousable. Not CRS, not pediatric CAPD, and not the 10-item ICE test. magent does not perform ICE testing or examine the patient. Not a medical device.

## Output

Returns the overall ICANS grade (0–4) as the maximum severity across the five domains (ICE, depressed LOC, seizure, deep focal motor weakness, ICP/edema), along with per-domain grade values, consistent with Lee 2019 Table 6 criteria.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "ice_score",
      "loc",
      "seizure",
      "motor_weakness",
      "icp"
     ],
     "properties": {
      "icp": {
       "enum": [
        "none",
        "focal_edema",
        "diffuse_edema"
       ],
       "type": "string",
       "description": "Caller-assigned raised intracranial pressure / cerebral edema (Lee 2019 Table 6): none (domain 0); focal_edema (focal/local edema on neuroimaging, 3); diffuse_edema (diffuse cerebral edema on imaging, or decerebrate/decorticate posturing, cranial nerve VI palsy, papilledema, or Cushing triad, 4). Case-insensitive. magent does not read imaging or examine the patient."
      },
      "loc": {
       "enum": [
        "none",
        "spontaneous",
        "voice",
        "tactile",
        "unarousable"
       ],
       "type": "string",
       "description": "Caller-assigned depressed level of consciousness (Lee 2019 Table 6): none (no depressed LOC, domain 0); spontaneous (awakens spontaneously, 1); voice (awakens to voice, 2); tactile (awakens only to tactile stimulus, 3); unarousable (unarousable or requires vigorous or repetitive tactile stimuli; stupor or coma, 4). Case-insensitive. magent does not examine the patient."
      },
      "seizure": {
       "enum": [
        "none",
        "rapidly_resolving",
        "life_threatening"
       ],
       "type": "string",
       "description": "Caller-assigned seizure (Lee 2019 Table 6): none (domain 0); rapidly_resolving (any clinical seizure, focal or generalized, that resolves rapidly, or nonconvulsive seizures on EEG that resolve with intervention, 3); life_threatening (life-threatening prolonged seizure >5 min or repetitive clinical or electrical seizures without return to baseline, 4). Case-insensitive. magent does not interpret EEG."
      },
      "ice_score": {
       "type": "integer",
       "description": "Caller-assigned Immune Effector Cell-Associated Encephalopathy
… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/astct-icans-consensus-grade-calculator-adult-lee-2019-0145a5c9/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)