# UniProt Protein Sequences and Function Lookup

> UniProt Protein Sequences and Function Lookup is a paid API for AI agents from bio.memoryapi.org, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Retrieves UniProt protein data including accession number, gene name, sequence length, organism, and function summary for a given protein.

## Facts

- Endpoint: GET https://bio.memoryapi.org/x402/bio/uniprot
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/bio-memoryapi-org-35b451e8
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_lKnr3sdaOdnThzRZYpdDJ

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability bio-memoryapi-org-35b451e8
```

Example prompt: Can you look up the UniProt entry for BRCA1 — I need the accession number, gene name, sequence length, organism, and a summary of what the protein does?

## When to prefer this

Use this endpoint when you need canonical protein metadata from UniProt — including function summaries, gene names, organism, and sequence length — for a known protein accession or gene name. Prefer this over PDB (3D structure), ChEMBL (bioactivity), or PubChem (small molecules) when the primary need is protein identity and function annotation.

## Known failure modes

- Unknown or invalid accession/gene name returns empty result or 404
- Ambiguous gene name matching multiple entries may return unexpected record
- Non-human organism proteins may have limited functional annotations
- Payment failure via x402 protocol returns 402 before data is served

## How this service works

UniProt protein sequences and function data — accession, gene name, sequence length, organism, and function summary.

## Output

Returns structured UniProt data for the requested protein including the UniProt accession number, gene name, amino acid sequence length, organism of origin, and a functional summary describing the protein's biological role.

## Example request

```json
{
 "name": "metformin",
 "type": "label"
}
```

## Request schema (JSON Schema)

```json
{
 "properties": {
  "input": {
   "properties": {
    "method": {
     "type": "string",
     "enum": [
      "GET"
     ]
    }
   },
   "required": [
    "method"
   ]
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/bio-memoryapi-org-35b451e8/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from bio.memoryapi.org](https://www.zero.xyz/host/bio.memoryapi.org/llms.txt)