# FDA Drug Approval History & NDA Applications

> FDA Drug Approval History & NDA Applications is a paid API for AI agents from bio.memoryapi.org, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Returns FDA drug approval history including NDA application numbers, applicants, brand names, dosage forms, and first approval dates.

## Facts

- Endpoint: GET https://bio.memoryapi.org/x402/bio/approvals
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/bio-memoryapi-org-bab56a26
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_j8fb8I0MUe1ixwuOSuTpZ

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability bio-memoryapi-org-bab56a26
```

Example prompt: Can you look up the FDA approval history for Lipitor — I want to know the NDA application number, which company applied, the approved dosage forms, and when it was first approved?

## When to prefer this

Use this endpoint when you need official FDA regulatory approval metadata — application numbers, sponsors, approval dates, and dosage forms — rather than clinical or pharmacological data. Prefer this over OpenFDA label or ChEMBL endpoints when the primary need is regulatory/approval history rather than drug safety labels, bioactivity, or chemical structure.

## Known failure modes

- Drug name not found in FDA database — returns empty or null results
- Ambiguous drug name matching multiple entries — may return multiple records requiring filtering
- API payment failure (x402) — returns 402 Payment Required
- Invalid query parameter format — returns 400 Bad Request
- FDA data unavailable or upstream outage — returns 503 or timeout

## How this service works

FDA drug approval history and NDA applications — application number, applicant, brand name, dosage form, first approval date.

## Output

Returns structured FDA drug approval records including NDA application number, applicant/sponsor name, brand name, approved dosage form(s), and the date of first FDA approval.

## Example request

```json
{
 "name": "metformin",
 "type": "label"
}
```

## Request schema (JSON Schema)

```json
{
 "properties": {
  "input": {
   "properties": {
    "method": {
     "type": "string",
     "enum": [
      "GET"
     ]
    }
   },
   "required": [
    "method"
   ]
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/bio-memoryapi-org-bab56a26/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from bio.memoryapi.org](https://www.zero.xyz/host/bio.memoryapi.org/llms.txt)