# Biomedical Funding Trend

> Biomedical Funding Trend is a paid API for AI agents from biomedical-grants.use.x402atlas.com, paid per call via x402, $0.03/call, status unknown (last checked 2026-10-28).

Returns year-by-year NIH project counts and dollar amounts for a search topic, with optional filters for institute, activity code, and award mechanism, over up to 10 fiscal years.

## Facts

- Endpoint: GET https://biomedical-grants.use.x402atlas.com/trend?utm_source=zero.xyz
- Price: $0.03/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-28
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/biomedical-funding-trend-8c106b40
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_DMsHNhz4zZyazcWrweCfF

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability biomedical-funding-trend-8c106b40
```

Example prompt: Show me the NIH funding trend for 'CRISPR gene editing' from fiscal year 2015 to 2024, broken down by year — just NCI grants, all mechanisms, so I can see whether project counts and dollar totals are growing.

## When to prefer this

Use this endpoint when you need time-series NIH funding data for a specific research topic — showing whether investment is growing, plateauing, or declining across fiscal years. Prefer it over the grant search endpoint when the goal is trend analysis rather than finding individual projects, and over the awards feed when you need multi-year historical context rather than recent additions. Ideal for market research, grant strategy, or investment due diligence in life sciences.

## Known failure modes

- Query matches no NIH projects — returns empty years array with a note field
- Fiscal year range exceeds 10-year window — request rejected
- Invalid institute abbreviation or activity code — may return empty results or error
- Current fiscal year data marked incomplete (complete: false) because awards are still being processed
- Rate limit or payment failure at $0.03 per call

## How this service works

NIH funding trend — how many projects and how many dollars NIH put into a topic each fiscal year over up to ten years, with institute, activity code and SBIR/STTR filters. Use to see whether money in a field is growing, when it moved, or how small-business awards on a topic trend before investing research effort or capital.

## Output

A JSON object containing the echoed query parameters, an as_of timestamp, and a years array where each element includes the fiscal_year, number of projects funded, total dollars awarded (in USD), and a boolean indicating whether that year's data is complete. Also includes aggregate total_projects and total_awarded across the full range, plus optional notes for incomplete or empty results.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [
      "query"
     ],
     "properties": {
      "to": {
       "type": "integer",
       "minimum": 1985,
       "description": "Last fiscal year; default the current one. At most 10 years from `from`"
      },
      "from": {
       "type": "integer",
       "minimum": 1985,
       "description": "First fiscal year; default four years before the current one"
      },
      "query": {
       "type": "string",
       "maxLength": 200,
       "description": "Words to match in title, abstract and terms; all must match"
      },
      "agency": {
       "type": "string",
       "maxLength": 40,
       "description": "Comma-separated NIH institute abbreviations, up to 5, e.g. NCI,NIAID"
      },
      "mechanism": {
       "enum": [
        "sbir",
        "grant",
        "contract"
       ],
       "type": "string",
       "description": "sbir = SBIR/STTR small-business awards; grant = other grants; contract = R&D contracts; omitted = all"
      },
      "activity_code": {
       "type": "string",
       "maxLength": 30,
       "description": "Comma-separated activity codes, up to 5, e.g. R01,U01,K08"
      }
     },
     "additionalProperties": false
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object",
     "required": [
      "as_of",
      "source",
      "caveat",
      "modified",
      "query",
      "from",
      "to",
      "agency",
      "activity_code",
      "mechanism",
      "years",
      "total_projects",
      "total_awarded"
     ],
     "properties": {
      "to": {
       "type": "integer"
      },
      "from": {
       "type": "integer"
      },
      "note": {
       "type": "string",
       "description": "Present on a sample, an empty result or when a year is incomplete"
      },
      "as_of": {
       "type": "string",
       "format": "date-time",
       "description": "Retrieval time, UTC"
      },
      "query": {
       "type": "string
… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/biomedical-funding-trend-8c106b40/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from biomedical-grants.use.x402atlas.com](https://www.zero.xyz/host/biomedical-grants.use.x402atlas.com/llms.txt)