# CARG Toxicity Score Calculator (Hurria 2011) > CARG Toxicity Score Calculator (Hurria 2011) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15). Computes the Cancer and Aging Research Group (CARG) chemotherapy toxicity score from 11 caller-supplied clinical flags and returns risk category (low/intermediate/high) with predicted grade 3–5 toxicity probability. ## Facts - Endpoint: GET https://api.magentlab.com/api/calc/carg_tt - Price: $0.005/call - Payment: x402 - Status: unknown - Last checked: 2026-09-15 - Activations on Zero: 0 - Tags: x402 - Canonical page: https://www.zero.xyz/c/carg-toxicity-score-calculator-hurria-2011-dcf21817 - Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_eZVqN4ozaovaLS1QkMEX8 Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently. ## How to call it through Zero Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`): ```sh zero fetch --capability carg-toxicity-score-calculator-hurria-2011-dcf21817 ``` Example prompt: Calculate the CARG chemo toxicity score for a 76-year-old male with GI cancer, hemoglobin of 9.8 g/dL, Jelliffe CrCl of 28 mL/min, planned for standard-dose polychemotherapy, who had one fall in the last 6 months, rates his hearing as fair, needs help with his medications, and has had decreased social activity — he can still walk a full block. ## When to prefer this Use this endpoint when you need the original Hurria 2011 CARG Table 5 integer score for geriatric oncology patients being considered for chemotherapy. Prefer it over general risk calculators when the clinical workflow requires an explicit toxicity risk tier (low/intermediate/high) with the published toxicity probabilities. Note that this is not the 2016 revised CARG, not CRASH, and does not generate chemotherapy orders or compute Jelliffe CrCl — those inputs must be supplied by the caller. ## Known failure modes - Missing required query parameter returns 400 error — all 12 fields are mandatory - Out-of-range hemoglobin (outside 3–22 g/dL) or age (outside 18–120) rejected - Invalid enum value for sex (must be 'male' or 'female') causes validation error - Caller must supply Jelliffe CrCl — magent does not compute it from creatinine/demographics - Boolean fields passed as strings instead of true/false may cause parse errors - This endpoint implements 2011 Hurria, not the 2016 revision — results will differ from tools using updated weights ## How this service works Hurria 2011 Table 5 CARG toxicity: age ≥72 (+2), GI/GU (+2, not inverted), standard dose (+2), polychemotherapy (+2), Hb male <11 or female <10 g/dL (+3), caller-assigned Jelliffe CrCl <34 (+3; magent does not compute Jelliffe), hearing fair/worse (+2), ≥1 fall in 6 months (+3), limited walking 1 block (+2), help with meds (+1), decreased social activity (+1). Max 19. 0-5 low 30%, 6-9 intermediate 52%, 10-19 high 83%. Not the 2016 revision, not CRASH, not a chemo order. ## Output Returns the integer CARG total score (0–19), the risk tier (low 0–5, intermediate 6–9, or high 10–19), and the associated predicted grade 3–5 chemotherapy toxicity probability (approximately 30%, 52%, or 83% respectively), based on the Hurria 2011 Table 5 derivation cohort. ## Request schema (JSON Schema) ```json { "type": "object", "$schema": "https://json-schema.org/draft/2020-12/schema", "required": [ "input" ], "properties": { "input": { "type": "object", "required": [ "type", "method" ], "properties": { "type": { "type": "string", "const": "http" }, "method": { "enum": [ "GET", "HEAD", "DELETE" ], "type": "string" }, "headers": { "type": "object", "additionalProperties": { "type": "string" } }, "queryParams": { "type": "object", "required": [ "age", "gi_or_gu", "standard_dose", "polychemotherapy", "hemoglobin_g_dl", "sex", "jelliffe_crcl_ml_min", "hearing_fair_or_worse", "falls_last_6_months", "limited_walking_one_block", "needs_help_with_medications", "decreased_social_activity" ], "properties": { "age": { "type": "integer", "description": "Age in years (18-120). Hurria 2011 Table 5: ≥72 scores 2. Derived in patients ≥65; magent still applies the ≥72 rule at any accepted age." }, "sex": { "enum": [ "female", "male" ], "type": "string", "description": "Sex used for the hemoglobin cutoff (female or male). Male <11 g/dL or female <10 g/dL scores 3." }, "gi_or_gu": { "type": "boolean", "description": "GI or GU cancer as assigned by the caller (Hurria 2011 Table 5). true scores 2. Lung, breast, GYN, and other cancers are 0. This is a risk factor present (+2), not inverted. magent does not assign cancer type from histology text." }, "standard_dose": { "type": "boolean", "description": "Standard chemotherapy dose as assigned by the caller (Hurria 2011 Table 5). true scores 2. Dose-reduced is 0. magent does not read a chemo order." }, "hemoglobin_g_dl": { "type": "number", "description": "Hemoglobin in g/dL (3-22). Male <11 or female <10 scores 3 (Hurria 2011 Table 5). 11.0 male and 10.0 female do not score." }, "polychemotherapy": { "type": "boolean", "description": "Polychemotherapy as assigned by the caller (Hurria 2011 Table 5). true scores 2." }, "falls_last_6_months": { "type": "boolean", "description": "≥1 fall in the last 6 months as assigned by the caller (Hurria 2011 Table 5). true scores 3. magent does not take a fall history." }, "j … (truncated) ``` ## More - Live health (JSON, refreshed every minute): https://www.zero.xyz/c/carg-toxicity-score-calculator-hurria-2011-dcf21817/health.json - [Zero catalog index](https://www.zero.xyz/llms.txt) - [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)