# Catalyst Pharma Regulatory Calendar

> Catalyst Pharma Regulatory Calendar is a paid API for AI agents from x402helper.xyz, paid per call via x402, $0.039/call, status unknown (last checked 2026-10-31).

Retrieves upcoming and past FDA regulatory events (PDUFA dates, AdComm meetings, CRL actions, priority reviews) for a given pharmaceutical company by ticker or CIK.

## Facts

- Endpoint: GET https://x402helper.xyz/89e509/catalyst/calendar?utm_source=zero.xyz
- Price: $0.039/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-31
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/catalyst-pharma-regulatory-calendar-f199b809
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_uqdyrk1OfRYHi1ketFUTk

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability catalyst-pharma-regulatory-calendar-f199b809
```

Example prompt: What are all the upcoming FDA regulatory events for Scholar Rock — their ticker is SRRK — including PDUFA dates, AdComm meetings, and any priority reviews?

## When to prefer this

Use this endpoint when you need structured FDA regulatory event data keyed to a specific pharmaceutical or biotech company, especially PDUFA dates, AdComm schedules, and CRL history. Prefer this over general web search when you need machine-readable, structured calendar data suitable for downstream analysis, alerting, or financial modeling. It is particularly valuable for clinical-stage biotech research where upcoming FDA decisions are key investment or monitoring catalysts.

## Known failure modes

- Unknown or invalid ticker symbol returns empty results or an error
- CIK not found in SEC EDGAR returns no events
- Payment not received or x402 payment header missing returns 402 Payment Required
- Lookback days exceeding 730 returns a validation error
- No regulatory events found within the specified date range returns an empty result set
- Network timeout or upstream data unavailability returns a 503 or empty response

## How this service works

X402 micropayments server — AI agents pay USDC for OFAC screening, rates, and billing verification.

## Output

Returns a JSON object with a list of FDA regulatory calendar events for the specified company, each including the event type (PDUFA, AdComm, CRL, priority review, or PDUFA extension), date, drug/program name if available, and related metadata. Future events are included by default; historical events are available within the configured lookback window.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [],
     "properties": {
      "cik": {
       "type": "string",
       "default": null,
       "description": "SEC EDGAR issuer CIK, any zero-padding accepted"
      },
      "ticker": {
       "type": "string",
       "default": null,
       "description": "Stock ticker symbol, e.g. SRRK"
      },
      "event_types": {
       "type": "array",
       "items": {
        "enum": [
         "pdufa",
         "adcomm",
         "crl",
         "priority_review",
         "pdufa_extension"
        ],
        "type": "string"
       },
       "default": null,
       "description": "Optional filter of regulatory event types to include (default all)"
      },
      "forward_only": {
       "type": "boolean",
       "default": null,
       "description": "Only future dates (default true)"
      },
      "lookback_days": {
       "type": "integer",
       "default": null,
       "maximum": 730,
       "minimum": 1,
       "description": "How far back to search filings, default 270"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "result": {},
  "success": true
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/catalyst-pharma-regulatory-calendar-f199b809/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from x402helper.xyz](https://www.zero.xyz/host/x402helper.xyz/llms.txt)