# ClearCheck Drug Adverse Events

> ClearCheck Drug Adverse Events is a paid API for AI agents from loonie-toll.onrender.com, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Returns FDA adverse event report counts for a drug, including total reports, top reactions, serious outcomes, and death statistics.

## Facts

- Endpoint: GET https://loonie-toll.onrender.com/adverse
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/clearcheck-drug-adverse-events-50b4bf26
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_cTOAXgIxXV5PdKHB8ikl1

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability clearcheck-drug-adverse-events-50b4bf26
```

Example prompt: How many adverse events have been reported for metformin in the FDA system, and what are the top 5 most common reactions along with how many of those reports involved serious outcomes or deaths?

## When to prefer this

Use this endpoint when you need a quick structured summary of FDA adverse event reporting data for a specific drug, including serious outcome and death statistics, without having to query the raw FAERS API directly. Prefer this over manual FAERS searches when building automated drug safety checks, content pipelines, or health research tools that need parsed, verdict-annotated results.

## Known failure modes

- Drug name not found in FAERS database returns zero counts or empty results
- Misspelled or brand-name vs generic name mismatches may return unexpected results
- FDA FAERS data has known underreporting bias — results reflect submitted reports, not true incidence
- Network timeout or service unavailability on the Render-hosted endpoint
- Invalid or missing 'drug' query parameter returns an error

## How this service works

Reported adverse event counts for a drug: total reports, top reactions, serious outcomes and deaths reported.

## Output

Returns a JSON object with the queried drug name, counts (totalReports, seriousReports, seriousSharePct, deathReports, deathSharePct), an array of top reactions with individual report counts and share percentages, a verdict string summarizing risk level, a disclaimer, the data source, and a retrievedAt timestamp.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [
      "drug"
     ],
     "properties": {
      "top": {
       "type": "integer",
       "description": "How many top reactions to return, default 10"
      },
      "drug": {
       "type": "string",
       "description": "Drug or product name as reported"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object",
     "properties": {
      "drug": {
       "type": "string"
      },
      "counts": {
       "type": "object",
       "properties": {
        "deathReports": {
         "type": "integer"
        },
        "totalReports": {
         "type": "integer"
        },
        "deathSharePct": {
         "type": "number"
        },
        "seriousReports": {
         "type": "integer"
        },
        "seriousSharePct": {
         "type": "integer"
        }
       }
      },
      "source": {
       "type": "string"
      },
      "reasons": {
       "type": "array",
       "items": {
        "type": "string"
       }
      },
      "verdict": {
       "type": "string"
      },
      "disclaimer": {
       "type": "string"
      },
      "retrievedAt": {
       "type": "string"
      },
      "topReactions": {
       "type": "array",
       "items": {
        "type": "object",
        "properties": {
         "reports": {
          "type": "integer"
         },
         "reaction": {
          "type": "string"
         },
         "shareOfReportsPct": {
          "type": "number"
         }
        }
       }
      }
     }
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/clearcheck-drug-adverse-events-50b4bf26/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from loonie-toll.onrender.com](https://www.zero.xyz/host/loonie-toll.onrender.com/llms.txt)