# ClinicalTrials.gov Recent Updates Feed

> ClinicalTrials.gov Recent Updates Feed is a paid API for AI agents from clinical.memoryapi.org, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Returns recently updated clinical trials across any disease area, including status changes, new results, and enrollment updates.

## Facts

- Endpoint: GET https://clinical.memoryapi.org/x402/clinical/updates
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/clinical-memoryapi-org-09dc1aa6
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_AI2YbYEmnllA2b7DK9N6V

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability clinical-memoryapi-org-09dc1aa6
```

Example prompt: Pull the most recent ClinicalTrials.gov updates for Alzheimer's disease trials — I want to see any status changes, new results, or enrollment updates that have come through lately.

## When to prefer this

Use this endpoint when you need a continuous or periodic feed of clinical trial activity rather than searching for a specific known trial. Ideal for competitive intelligence workflows, research monitoring bots, and alerting pipelines that need to detect changes across a disease landscape without querying individual NCT IDs.

## Known failure modes

- No recent updates found for the specified disease area — empty result set returned
- Invalid or unsupported disease area filter causes 400 bad request
- Payment not processed via x402 results in 402 Payment Required
- Rate limiting or server overload returns 429 or 503
- Stale cache may cause delayed visibility of very recent updates

## How this service works

Recently updated clinical trials. Monitor for status changes, new results, enrollment updates in any disease area.

## Output

A list of recently updated clinical trials with details on what changed — including trial NCT IDs, titles, disease areas, updated status, enrollment figures, newly posted results, and timestamps of the updates.

## Example request

```json
{
 "limit": 10,
 "updateType": "all",
 "diseaseArea": "Alzheimer's disease"
}
```

## Request schema (JSON Schema)

```json
{
 "properties": {
  "input": {
   "required": [
    "method"
   ],
   "properties": {
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/clinical-memoryapi-org-09dc1aa6/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clinical.memoryapi.org](https://www.zero.xyz/host/clinical.memoryapi.org/llms.txt)