# Clinical Trials Pipeline Query — x402 Micropayment Endpoint

> Clinical Trials Pipeline Query — x402 Micropayment Endpoint is a paid API for AI agents from x402helper.xyz, paid per call via x402, $0.039/call, status unknown (last checked 2026-10-31).

Returns clinical trial pipeline data (by condition, drug/molecule, or sponsor) filtered to a near-term readout window, accessible via USDC micropayment.

## Facts

- Endpoint: GET https://x402helper.xyz/89e509/trials/pipeline?utm_source=zero.xyz
- Price: $0.039/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-31
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/clinical-trials-pipeline-query-x402-micropayment-endpoint-59a90be7
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_QXh-IoXy0CKaW4tUIrI-y

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability clinical-trials-pipeline-query-x402-micropayment-endpoint-59a90be7
```

Example prompt: Can you pull up clinical trial pipeline readouts for Merck as the sponsor, focused on oncology indications, with readouts expected in the next 90 days?

## When to prefer this

Use this endpoint when you need programmatic, pay-per-query access to clinical trial pipeline data filtered by drug, indication, or sponsor with a configurable near-term readout window. It is well-suited for AI agents doing biotech research, catalyst tracking, or investment analysis that require fresh trial data without a subscription. Prefer this over static databases when you need recent readout windows and are working within an x402 micropayment-capable agent framework.

## Known failure modes

- Payment not included or insufficient — returns HTTP 402 requiring USDC payment
- No trials found matching the specified filters — empty result set returned
- Invalid window_days value outside 1–730 range — validation error
- Missing required 'type' or 'method' fields — schema validation error
- Upstream trial data source unavailable — server error or timeout

## How this service works

X402 micropayments server — AI agents pay USDC for OFAC screening, rates, and billing verification.

## Output

A JSON object with a 'success' boolean and a 'result' object containing clinical trial pipeline records matching the query filters (condition, intervention, sponsor, and readout window). Exact fields depend on available trial data.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [],
     "properties": {
      "cond": {
       "type": "string",
       "default": null,
       "description": "Condition or indication"
      },
      "intr": {
       "type": "string",
       "default": null,
       "description": "Intervention, drug or molecule name"
      },
      "spons": {
       "type": "string",
       "default": null,
       "description": "Sponsor or company name"
      },
      "window_days": {
       "type": "integer",
       "default": null,
       "maximum": 730,
       "minimum": 1,
       "description": "Near-term readout window in days, default 180"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "result": {},
  "success": true
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/clinical-trials-pipeline-query-x402-micropayment-endpoint-59a90be7/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from x402helper.xyz](https://www.zero.xyz/host/x402helper.xyz/llms.txt)