# ClinicalIntelPulse Pipeline Scan

> ClinicalIntelPulse Pipeline Scan is a paid API for AI agents from clinicalintelpulse.theaslangroupllc.com, paid per call via x402, $0.15/call, status unknown (last checked 2026-09-16).

Scans the global clinical trial pipeline for any disease, returning active Phase 2/3 trial counts, sponsor landscape, geographic distribution, mechanism breakdown, and pipeline density across 400,000+ trials.

## Facts

- Endpoint: GET https://clinicalintelpulse.theaslangroupllc.com/api/clinical/pipeline-scan
- Price: $0.15/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-16
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/clinicalintelpulse-pipeline-scan-a5eb7c01
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_T4T_jAvF4KJ3jiNI9mXpg

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability clinicalintelpulse-pipeline-scan-a5eb7c01
```

Example prompt: Run a full clinical trial pipeline scan for non-alcoholic steatohepatitis — I want to see all active Phase 2 and Phase 3 trials, the sponsor landscape, which mechanisms are being tested, and how geographically spread the activity is.

## When to prefer this

Use this endpoint when you need a broad, high-level pipeline overview for a disease area — covering trial volume, sponsor competitive landscape, mechanism diversity, and geographic spread all in one call. Prefer this over single-trial deep-dive endpoints when the goal is strategic intelligence for biotech investing, competitive benchmarking, or pharma market analysis rather than details on a specific trial.

## Known failure modes

- Unknown or misspelled disease name returns empty results or a 400 error
- Very rare diseases with minimal trial activity return sparse data
- Network timeout on large disease areas with thousands of trials
- 402 Payment Required if USDC payment is not included or insufficient
- Rate limiting if called too frequently in succession

## How this service works

Clinical trial pipeline scan for any disease — all active Phase 2/3 trials with trial counts, sponsor landscape, geographic distribution, mechanism breakdown and pipeline density, across 400,000+ trials worldwide. For biotech-investing and pharma agents.

## Output

Returns an aggregated pipeline report including: total count of active Phase 2/3 trials for the queried disease, list of sponsors and their trial counts, geographic distribution by country/region, breakdown of drug mechanisms of action under investigation, and an overall pipeline density score — drawn from a database of 400,000+ global trials.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "lang": {
       "type": "string"
      },
      "phase": {
       "type": "string"
      },
      "status": {
       "type": "string"
      },
      "condition": {
       "type": "string"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "errors": {
     "type": "object",
     "description": "Documented error responses, keyed by HTTP status code",
     "additionalProperties": {
      "type": "object",
      "required": [
       "description"
      ],
      "properties": {
       "example": {
        "type": "object"
       },
       "description": {
        "type": "string"
       }
      }
     }
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "query_summary": {
   "condition": "Non-Small Cell Lung Cancer",
   "status_filter": "RECRUITING,ACTIVE_NOT_RECRUITING",
   "phases_searched": [
    "PHASE2",
    "PHASE3"
   ]
  },
  "pipeline_totals": {
   "phase2_count": 156,
   "phase3_count": 89,
   "total_active": 245
  },
  "phase3_highlights": [
   {
    "nctId": "NCT05116748",
    "title": "Pembrolizumab + Carboplatin vs SOC in NSCLC",
    "status": "RECRUITING",
    "sponsor": "Merck",
    "countries": [
     "United States",
     "Germany",
     "Japan",
     "South Korea"
    ],
    "primaryCompletion": "2026-03"
   }
  ],
  "sponsor_landscape": {
   "academic_sponsors": "ECOG-ACRIN, Alliance, NCI leading academic cooperative groups",
   "emerging_biotechs": [
    "Turning Point Therapeutics",
    "Blueprint Medicines",
    "Mirati Therapeutics"
   ],
   "top_industry_sponsors": [
    "Roche/Genentech (18 trials)",
    "Bristol-Myers Squibb (14)",
    "AstraZeneca (13)",
    "Merck (12)",
    "Pfizer (11)"
   ]
  },
  "mechanism_breakdown": {
   "adc": 18,
   "other": 81,
   "bispecific": 12,
   "targeted_therapy": 41,
   "chemo_combinations": 31,
   "io_checkpoint_inhibitors": 62
  },
  "pipeline_assessment": "Extremely crowded pipeline — PD-1/L1 space saturated. ADCs and bispecifics represent highest differentiation potential. KRAS G12C targeted therapies emerging as new standard.",
  "approved_drugs_context": "NSCLC has 30+ FDA-approved agents. Pipeline is additive rather than disruptive in most cases.",
  "geographic_distribution": {
   "asia_pct": 22,
   "other_pct": 5,
   "europe_pct": 28,
   "us_trials_pct": 45,
   "most_active_countries": [
    "United States",
    "China",
    "Germany",
    "South Korea",
    "Japan"
   ]
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/clinicalintelpulse-pipeline-scan-a5eb7c01/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clinicalintelpulse.theaslangroupllc.com](https://www.zero.xyz/host/clinicalintelpulse.theaslangroupllc.com/llms.txt)