# Cochrane Systematic Review Search via PubMed

> Cochrane Systematic Review Search via PubMed is a paid API for AI agents from api.healthtravel-api.workers.dev, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-29).

Searches PubMed for Cochrane systematic reviews matching a query term and returns citation records (PMID, title, DOI, publication date) — up to 10 results per call.

## Facts

- Endpoint: GET https://api.healthtravel-api.workers.dev/api/health/clinical-evidence-cochrane?utm_source=zero.xyz
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-29
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/cochrane-systematic-review-search-via-pubmed-8b1bd1e4
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_7JtxJvGgP33JO_OSdL26V

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability cochrane-systematic-review-search-via-pubmed-8b1bd1e4
```

Example prompt: Can you search Cochrane systematic reviews for evidence on metformin for type 2 diabetes and give me the top 5 most recent citations with their PMIDs and DOIs?

## When to prefer this

Use this endpoint when you need authoritative, high-quality systematic review citations from the Cochrane Database sourced via PubMed — ideal for evidence-based medicine tasks, literature research, or clinical decision support. Prefer this over general web searches when you specifically need Cochrane-level meta-analytic evidence with structured citation metadata (PMID, DOI). Not suitable when you need full abstracts, full-text access, or non-Cochrane literature.

## Known failure modes

- Query string shorter than 2 or longer than 100 characters returns a validation error
- No matching Cochrane reviews found returns an empty reviews array with total: 0
- PubMed API unavailability causes a gateway or timeout error
- Max parameter outside 1–10 range may be rejected or clamped
- Highly ambiguous or misspelled query terms may return zero or irrelevant results

## How this service works

Cochrane systematic reviews of health interventions, found through PubMed (journal Cochrane Database Syst Rev): PMID, title, publication date and DOI for a search term. Citation records only (no abstract, no full text). Up to 10 per call.

## Output

A JSON object containing the search query, total number of matching Cochrane reviews in PubMed, the source URL, a timestamp, and an array of up to 10 citation records each with PMID, PubMed URL, DOI, title, and publication date. No abstracts or full text are included.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [
      "q"
     ],
     "properties": {
      "q": {
       "type": "string",
       "description": "Search words, letters, digits, spaces and hyphens, 2 to 100 characters"
      },
      "max": {
       "type": "string",
       "description": "How many reviews, 1 to 10 (default 5)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "query": "aspirin",
  "total": 192,
  "source": "https://pubmed.ncbi.nlm.nih.gov/",
  "reviews": [
   {
    "doi": "10.1002/14651858.CD015266.pub3",
    "url": "https://pubmed.ncbi.nlm.nih.gov/41919561/",
    "pmid": "41919561",
    "title": "Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) for preventing colorectal cancer and colorectal adenoma in the general population.",
    "published": "2026 Apr 1"
   },
   {
    "doi": "10.1002/14651858.CD015266.pub2",
    "url": "https://pubmed.ncbi.nlm.nih.gov/41740630/",
    "pmid": "41740630",
    "title": "Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) for preventing colorectal cancer and colorectal adenoma in the general population.",
    "published": "2026 Feb 26"
   }
  ],
  "checkedAt": "2026-10-23T09:36:34.601Z"
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/cochrane-systematic-review-search-via-pubmed-8b1bd1e4/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.healthtravel-api.workers.dev](https://www.zero.xyz/host/api.healthtravel-api.workers.dev/llms.txt)