# CRISPR Research Query API

> CRISPR Research Query API is a paid API for AI agents from fiona-125b95be.base44.app, paid per call via x402, $1/call, status unknown (last checked 2026-09-15).

Answers research questions about CRISPR gene editing, base editing, prime editing, and gene therapy by synthesizing information with cited sources

## Facts

- Endpoint: POST https://fiona-125b95be.base44.app/functions/crisprQuery
- Price: $1/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/crispr-research-query-api-a46ac2d4
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_SznycZqZwSf0SqJ_6IoCk

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability crispr-research-query-api-a46ac2d4 -d '<json body>'
```

Example prompt: Can you research the latest advances in prime editing versus base editing for treating sickle cell disease, and return up to 15 cited sources?

## When to prefer this

Choose this endpoint when you need synthesized, citation-backed answers specifically about CRISPR gene editing, base editing, prime editing, or gene therapy — particularly when the user needs sourced scientific information rather than raw document retrieval or general web search.

## Known failure modes

- Missing required 'question' field returns a 400 or schema validation error
- Overly broad or ambiguous question may yield low-quality synthesis
- max_results set too high may time out or return incomplete data
- Payment failure (x402) blocks access if USDC payment is not completed
- External data sources unavailable may result in sparse or empty citations array

## How this service works

User Generated App

## Output

Returns a structured object containing the original question, a synthesized narrative answer on the CRISPR/gene editing topic, an array of source citations (each with URL, title, source name, and date), the topic label, timestamp, and the number of items searched.

## Example request

```json
{
 "question": "What are the latest developments in CRISPR gene editing for treating genetic diseases?",
 "max_results": 10
}
```

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "required": [
  "question"
 ],
 "properties": {
  "question": {
   "type": "string",
   "description": "Your research question about CRISPR gene editing, base editing, prime editing, or gene therapy"
  },
  "max_results": {
   "type": "number",
   "description": "Max results to return (default: 10)"
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "object",
 "properties": {
  "topic": {
   "type": "string"
  },
  "answer": {
   "type": "string",
   "description": "Synthesized CRISPR/gene editing research with citations"
  },
  "sources": {
   "type": "array",
   "items": {
    "type": "object",
    "properties": {
     "url": {
      "type": "string"
     },
     "date": {
      "type": "string"
     },
     "title": {
      "type": "string"
     },
     "source": {
      "type": "string"
     }
    }
   }
  },
  "question": {
   "type": "string"
  },
  "timestamp": {
   "type": "string"
  },
  "items_searched": {
   "type": "number"
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/crispr-research-query-api-a46ac2d4/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from fiona-125b95be.base44.app](https://www.zero.xyz/host/fiona-125b95be.base44.app/llms.txt)