# DIPSS Calculator for Primary Myelofibrosis (Passamonti 2010)

> DIPSS Calculator for Primary Myelofibrosis (Passamonti 2010) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-13).

Computes the Dynamic International Prognostic Scoring System (DIPSS) risk score and category for primary myelofibrosis using five clinical variables from Passamonti 2010

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/dipss
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-13
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/dipss-calculator-for-primary-myelofibrosis-passamonti-2010-562fb24a
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_JZqC5mJav9P-_JRdMK4W-

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability dipss-calculator-for-primary-myelofibrosis-passamonti-2010-562fb24a
```

Example prompt: Calculate the DIPSS score for a 70-year-old PMF patient with WBC 30×10^9/L, hemoglobin 9.2 g/dL, peripheral-blood blasts at 2%, and constitutional symptoms present — what's their risk category?

## When to prefer this

Use this endpoint when you need to calculate the original Passamonti 2010 DIPSS score specifically — not DIPSS Plus (which adds karyotype, transfusion dependence, and platelet count) and not aaDIPSS. Prefer this when working with the standard five-variable prognostic model for primary myelofibrosis, or when you need a validated, reproducible numeric score for clinical documentation, research, or triage workflows.

## Known failure modes

- Missing required query parameters (age, hemoglobin_g_dl, wbc_10e9_l, blasts_percent, constitutional_symptoms) returns a validation error
- Age outside 18–120, hemoglobin outside 3–20, WBC outside 0.1–500, or blasts outside 0–30 may return a 422 or similar validation error
- Boundary values (age exactly 65, WBC exactly 25, hemoglobin exactly 10, blasts exactly 0.9) score 0 per the ≤ arm as documented
- Constitutional symptoms must be boolean true/false — string values or missing field will cause an error
- Payment failure (x402) if USDC balance or HTTP 402 flow is not handled by the client

## How this service works

Passamonti 2010 DIPSS for primary myelofibrosis: age >65 (1), WBC >25×10^9/L (1), hemoglobin <10 g/dL (2), peripheral-blood blasts ≥1% (1), constitutional symptoms (1); max 6. Low 0, intermediate_1 1–2, intermediate_2 3–4, high 5–6. Not DIPSS Plus or aaDIPSS. magent does not read a smear; constitutional symptoms are caller-assigned.

## Output

Returns a JSON object with the computed DIPSS total score (integer 0–6) and a risk category label: Low (0 points), Intermediate-1 (1–2 points), Intermediate-2 (3–4 points), or High (5–6 points), based on the Passamonti 2010 scoring table.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "age",
      "hemoglobin_g_dl",
      "wbc_10e9_l",
      "blasts_percent",
      "constitutional_symptoms"
     ],
     "properties": {
      "age": {
       "type": "integer",
       "description": "Age in years (18-120). Age >65 scores 1 (Passamonti 2010 Table 3). Age 65 is the ≤65 arm and scores 0."
      },
      "wbc_10e9_l": {
       "type": "number",
       "description": "White-cell count in 10^9/L (0.1-500). >25 scores 1 (Passamonti 2010 Table 3). 25.0 is the ≤25 arm and scores 0. magent does not assay WBC."
      },
      "blasts_percent": {
       "type": "number",
       "description": "Peripheral-blood blasts as a percent (0-30). ≥1 scores 1 (Passamonti 2010 Table 3). 0.9 is the <1 arm and scores 0. magent does not read a smear."
      },
      "hemoglobin_g_dl": {
       "type": "number",
       "description": "Hemoglobin in g/dL (3-20). <10 scores 2 (Passamonti 2010 Table 3; anemia HR 4.18). 10.0 is the ≥10 arm and scores 0. magent does not assay hemoglobin."
      },
      "constitutional_symptoms": {
       "type": "boolean",
       "description": "Weight loss >10% in 6 months, night sweats, or unexplained fever >37.5°C as assigned by the caller (Passamonti 2010 methods). true scores 1. magent does not take a history."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/dipss-calculator-for-primary-myelofibrosis-passamonti-2010-562fb24a/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)