# Drug-Drug Interaction Checker

> Drug-Drug Interaction Checker is a paid API for AI agents from whatchuneed.vercel.app, paid per call via x402, $0.2/call, status unknown (last checked 2026-09-15).

Checks a list of drugs for known interactions, returning severity and description for each pair

## Facts

- Endpoint: POST https://whatchuneed.vercel.app/api/med/interactions
- Price: $0.2/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/drug-drug-interaction-checker-9372427d
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_QALOiDVGKqhgWWBLRniI1

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability drug-drug-interaction-checker-9372427d -d '<json body>'
```

Example prompt: Can you check for any interactions between warfarin, aspirin, and metformin, and tell me how severe they are?

## When to prefer this

Use this endpoint when you need a quick, pay-per-call drug interaction lookup without maintaining your own pharmacology database. Best for AI agents building health assistants, clinical decision support tools, or patient-facing medication safety apps that need structured severity + description output per drug pair.

## Known failure modes

- Unrecognized drug name returns empty or partial results
- Fewer than two drugs provided yields no interactions
- Drug name misspellings may not be resolved, returning no match
- Very new or rare drugs may not be in the database
- Empty interactions array returned if no known interactions exist

## How this service works

320+ pay-per-call API endpoints across accommodation, LLM, code execution, crypto, medical, finance, and more. One API, one payment. Powered by x402 protocol.

## Output

An array of interaction objects, each containing the names of the two interacting drugs, a severity rating (e.g. major, moderate, minor), and a plain-language description of the interaction and its clinical significance.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "required": [
  "drugs"
 ],
 "properties": {
  "drugs": {
   "type": "array"
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "object",
 "properties": {
  "interactions": {
   "type": "array",
   "items": {
    "type": "object",
    "properties": {
     "drug1": {
      "type": "string"
     },
     "drug2": {
      "type": "string"
     },
     "severity": {
      "type": "string"
     },
     "description": {
      "type": "string"
     }
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/drug-drug-interaction-checker-9372427d/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from whatchuneed.vercel.app](https://www.zero.xyz/host/whatchuneed.vercel.app/llms.txt)