# Dutch Lipid Clinic Network (DLCN) Familial Hypercholesterolaemia Score

> Dutch Lipid Clinic Network (DLCN) Familial Hypercholesterolaemia Score is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Calculates the Dutch Lipid Clinic Network (Nordestgaard 2013 Table 1) FH score from LDL cholesterol, family history, clinical history, physical findings, and DNA mutation status.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/dutch_fh
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/dutch-lipid-clinic-network-dlcn-familial-hypercholesterolaemia-score-f04bed09
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_M02njchKB5_pvWer6mfmm

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability dutch-lipid-clinic-network-dlcn-familial-hypercholesterolaemia-score-f04bed09
```

Example prompt: Calculate the Dutch Lipid Clinic Network FH score for a patient with an LDL of 5.8 mmol/L, premature coronary heart disease, a first-degree relative with premature CHD, no tendon xanthoma, no corneal arcus, no child with elevated LDL, no first-degree relative with LDL above the 95th percentile, no first-degree relative with xanthoma or arcus, and a confirmed causative LDLR mutation.

## When to prefer this

Use this endpoint when you need to programmatically apply the adult Dutch Lipid Clinic Network (Nordestgaard 2013 Table 1) FH scoring algorithm — not the Simon Broome, MEDPED, or homozygous FH criteria — and all clinical findings have already been assessed by a clinician or extracted from structured EHR data. Ideal for automating lipid clinic workflows, EHR decision-support, or risk-stratification pipelines where LDL and family/clinical/DNA flags are available as structured inputs.

## Known failure modes

- Missing required boolean flags returns a validation error
- Supplying both ldl_mmol_l and ldl_mg_dl simultaneously returns an error (exactly one must be provided)
- LDL value outside accepted range (mmol/L 1–20 or mg/dL 40–800) may be rejected or return an unexpected score
- Misclassified caller-assigned clinical findings (e.g., incorrect age cutoffs for premature CHD) produce an incorrect score — garbage-in-garbage-out with no server-side guard
- HTTP 402 returned if payment credentials are missing or invalid

## How this service works

Dutch Lipid Clinic Network (Nordestgaard 2013 Table 1) familial hypercholesterolaemia score. One LDL (mmol/L or mg/dL / 38.67) plus family, clinical, physical, and DNA groups; per group only the highest. Max 26. Definite >8, probable 6-8, possible 3-5, unlikely 0-2. Score 8 (mutation alone) is probable. Adult Table 1 only; not Simon Broome, not MEDPED, not homozygous FH. magent does not assay lipids, examine tendons or arcus, or sequence genes. Not a medical device and not a diagnosis of FH.

## Output

Returns the total DLCN FH score (0–26) broken down by group (lipid, family, clinical, physical, DNA), with per-group highest-item selection applied, plus a categorical FH probability label: definite (>8), probable (6–8), possible (3–5), or unlikely (0–2).

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "first_degree_premature_chd",
      "first_degree_ldl_gt_95th",
      "first_degree_xanthoma_or_arcus",
      "child_ldl_gt_95th",
      "premature_chd",
      "premature_cerebral_or_pvd",
      "tendon_xanthoma",
      "corneal_arcus_age_lt_45",
      "causative_mutation_ldlr_apob_pcsk9"
     ],
     "properties": {
      "ldl_mg_dl": {
       "type": "number",
       "description": "LDL cholesterol in mg/dL (40-800). Converted to mmol/L as mg/dL / 38.67, then scored on the mmol/L bands. Provide exactly one lipid parameter."
      },
      "ldl_mmol_l": {
       "type": "number",
       "description": "LDL cholesterol in mmol/L (1-20). Nordestgaard 2013 Table 1 bands: >8.5 → 8, 6.5-8.4 → 5, 5.0-6.4 → 3, 4.0-4.9 → 1. Provide exactly one of ldl_mmol_l or ldl_mg_dl. magent does not assay lipids."
      },
      "premature_chd": {
       "type": "boolean",
       "description": "Premature coronary heart disease in the subject (Nordestgaard 2013 Table 1 clinical history, 2 points; men <55 years / women <60 years as assigned by the caller). true or false. magent does not diagnose CHD or compute age or sex. If premature_cerebral_or_pvd is also true, the clinical group is 2, not 3."
      },
      "tendon_xanthoma": {
       "type": "boolean",
       "description": "Tendon xanthoma in the subject (Nordestgaard 2013 Table 1 physical examination, 6 points). true or false as assigned by the caller. magent does not examine tendons. If corneal_arcus_age_lt_45 is also true, the physical group is 6, not 10."
      },
      "child_ldl_gt_95th": {
       "type": "boolean",
       "description": "Child under 18 years with LDL cholesterol above the 95th percentile (Nordestgaard 2013 Table 1 family history, 2 points). true or false as assigned by the caller. magent does not assay lipids or take a pedigree."
      },
      "corneal_arcus_age_lt_45": {
       "type": "boolean",
       "description": "Arcus c
… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/dutch-lipid-clinic-network-dlcn-familial-hypercholesterolaemia-score-f04bed09/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)
