# EBI GWAS Catalog SNPs by Gene

> EBI GWAS Catalog SNPs by Gene is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Returns SNPs mapped to a gene from the EBI GWAS Catalog, given an HGNC gene symbol.

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/gwas-snps-by-gene
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/ebi-gwas-catalog-snps-by-gene-606bf4e5
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_rLmX2aZhnNx_DygkoflOv

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability ebi-gwas-catalog-snps-by-gene-606bf4e5 -d '<json body>'
```

Example prompt: Can you pull all the SNPs mapped to the BRCA2 gene from the EBI GWAS Catalog?

## When to prefer this

Use this endpoint when you need to quickly retrieve GWAS-mapped SNPs for a specific gene by its HGNC symbol, especially for bioinformatics pipelines, genomics research, or variant enrichment workflows where EBI GWAS Catalog data is the source of truth.

## Known failure modes

- Invalid or unrecognized HGNC gene symbol returns empty results or error
- Gene with no GWAS hits returns empty SNP list
- Missing gene parameter causes bad request response
- Network or upstream EBI API unavailability causes timeout or error

## How this service works

SNPs mapped to a gene in the EBI GWAS Catalog (param gene = HGNC symbol, e.g. BRCA2). Query: ?gene= Returns JSON.

## Output

A JSON payload listing SNPs (single nucleotide polymorphisms) that are mapped to the specified gene in the EBI GWAS Catalog, including variant identifiers and associated study metadata.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/ebi-gwas-catalog-snps-by-gene-606bf4e5/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)
