# EBI GWAS Catalog Studies by Trait

> EBI GWAS Catalog Studies by Trait is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Retrieves GWAS Catalog studies from the EBI database for a specified disease or trait term mapped to an EFO ontology concept

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/gwas-studies-by-trait
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/ebi-gwas-catalog-studies-by-trait-4faa7560
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_TxViglmuV72OdXZ1irLM3

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability ebi-gwas-catalog-studies-by-trait-4faa7560 -d '<json body>'
```

Example prompt: Can you pull up all the GWAS Catalog studies from EBI that are mapped to asthma as the trait?

## When to prefer this

Use this endpoint when you need to programmatically retrieve GWAS Catalog studies for a specific disease or trait using EFO ontology terminology. Ideal for bioinformatics pipelines, genomics research workflows, or when building applications that need to surface genetic association study data by phenotype. Prefer this over manual EBI GWAS Catalog browsing when automating trait-to-study lookups.

## Known failure modes

- Trait name not recognized or not mapped in EFO ontology — returns empty results or error
- Misspelled trait name yields no matches
- Ambiguous trait name matching multiple EFO terms may return partial results
- API timeout for traits with very large numbers of associated studies
- Payment not processed — 402 response before data is returned

## How this service works

EBI GWAS Catalog studies for a mapped EFO disease/trait term (param q = trait name, e.g. asthma). Query: ?q= Returns JSON.

## Output

A JSON array or object containing GWAS Catalog study records associated with the queried EFO-mapped trait, including study metadata such as publication details, author information, sample sizes, and association statistics.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/ebi-gwas-catalog-studies-by-trait-4faa7560/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)