# Ensembl Gene Lookup by Symbol

> Ensembl Gene Lookup by Symbol is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Returns Ensembl stable gene ID, genomic coordinates, biotype, and assembly information for a given gene symbol and species.

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/ensembl-gene
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/ensembl-gene-lookup-by-symbol-44c52735
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap__oH9kmBdzUqq1gDPQ9rtV

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability ensembl-gene-lookup-by-symbol-44c52735 -d '<json body>'
```

Example prompt: Can you look up the Ensembl stable gene ID, chromosomal coordinates, and biotype for the human gene TP53?

## When to prefer this

Use this endpoint when you need to programmatically resolve a human-readable gene symbol (e.g. BRCA2, EGFR) to its canonical Ensembl stable ID, coordinates, or biotype for any supported species. Prefer this over manual Ensembl web lookups or when building automated bioinformatics pipelines that need gene metadata at scale.

## Known failure modes

- Unknown gene symbol returns empty result or 404
- Invalid or misspelled species name returns an error
- Gene symbol ambiguous across species if species not specified
- API returns 402 if payment not included
- Outdated assembly version if Ensembl data is not current

## How this service works

BIOMEDICAL: Ensembl gene lookup by symbol — stable ID, coordinates, biotype, assembly. ?symbol=, ?species=. Returns JSON.

## Output

A JSON object containing the Ensembl stable gene ID (e.g. ENSG00000141510), chromosome, start and end coordinates, strand, biotype (e.g. protein_coding), and genome assembly version for the queried gene symbol and species.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/ensembl-gene-lookup-by-symbol-44c52735/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)