# FDA Adverse Event Reports

> FDA Adverse Event Reports is a paid API for AI agents from x402-filings.datalayer.workers.dev, paid per call via x402, $0.02/call, status unknown (last checked 2026-10-12).

Returns ranked adverse event reaction counts for a drug or medical device from the FDA FAERS and MAUDE systems, with report totals and interpretation caveats.

## Facts

- Endpoint: GET https://x402-filings.datalayer.workers.dev/v1/fda/adverse-events?utm_source=zero.xyz
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-12
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/fda-adverse-event-reports-55bc97fb
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_ut_ISVKErkuttOwgUrfnj

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability fda-adverse-event-reports-55bc97fb
```

Example prompt: Pull the top 20 most frequently reported adverse reactions for ibuprofen from the FDA FAERS database and include the total report count.

## When to prefer this

Use this endpoint when you need structured, ranked FDA pharmacovigilance signal data for a specific drug or medical device without building a direct FDA API integration. It is ideal for safety due diligence, regulatory research, competitive intelligence, or patient-facing drug information tools. Prefer this over direct FDA API access when you want pre-ranked reaction data with caveats included and per-call micropayment billing via x402.

## Known failure modes

- Drug or device name not found in FDA systems — returns empty results or zero reports
- Ambiguous name matching multiple drugs or devices — may return aggregated or unexpected results
- Limit parameter out of range (must be 1–50) — returns validation error
- Neither drug nor device parameter provided — required field missing error
- FDA data source temporarily unavailable — upstream service error

## How this service works

Adverse event reports for a drug or medical device from the FDA's FAERS and MAUDE systems: total report count and the most frequently reported reactions, ranked. Returns the interpretation caveat with the data — these are voluntary reports, a report does not establish causation, and counts scale with how widely a product is used.

## Output

Returns the total number of adverse event reports filed for the queried drug or device, a ranked list of the most frequently reported reactions (up to the requested limit), and a standard interpretation caveat noting that reports are voluntary, do not establish causation, and that counts scale with product usage prevalence.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "drug": {
       "type": "string",
       "examples": [
        "ibuprofen"
       ],
       "description": "Brand or generic drug name. Either drug or device is required."
      },
      "limit": {
       "type": "integer",
       "examples": [
        10
       ],
       "description": "Max ranked reactions, 1-50. Default 10."
      },
      "device": {
       "type": "string",
       "examples": [
        "insulin pump"
       ],
       "description": "Device generic name."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/fda-adverse-event-reports-55bc97fb/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from x402-filings.datalayer.workers.dev](https://www.zero.xyz/host/x402-filings.datalayer.workers.dev/llms.txt)