# FDA Drug Label Lookup — Interactions, Warnings & Contraindications

> FDA Drug Label Lookup — Interactions, Warnings & Contraindications is a paid API for AI agents from x402-endpoints.onrender.com, paid per call via x402, $0.05/call, status unknown (last checked 2026-09-15).

Looks up official FDA drug label information (interactions, warnings, contraindications) by generic or brand name via openFDA

## Facts

- Endpoint: GET https://x402-endpoints.onrender.com/drug/label
- Price: $0.05/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/fda-drug-label-lookup-interactions-warnings-contraindications-beb32e4a
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_nist-uo2cyl3Y36jZB2d_

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability fda-drug-label-lookup-interactions-warnings-contraindications-beb32e4a
```

Example prompt: Can you look up the official FDA drug label for metformin — specifically the warnings, drug interactions, and contraindications?

## When to prefer this

Use this endpoint when you need authoritative, official US FDA drug label data — specifically warnings, drug interactions, and contraindications — by drug name. Prefer this over general web search when regulatory accuracy matters, or when you need structured label data rather than summarized third-party content. Best for US-market drugs.

## Known failure modes

- Drug name not found in FDA database — no results returned
- Ambiguous drug name returning unrelated products
- Rate limiting or service unavailability on openFDA backend
- Invalid query parameter format returns error
- Limit parameter out of range (must be 1-10)

## How this service works

Drug interactions, warnings and contraindications lookup from the official FDA openFDA drug labels — by generic or brand name. Returns the key label sections. Coverage US.

## Output

Returns key sections from the official FDA drug label for the queried drug, including warnings, drug interactions, contraindications, and other label content. May return multiple labels if multiple products match (up to the specified limit).

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [
      "drug"
     ],
     "properties": {
      "drug": {
       "type": "string",
       "description": "Drug generic or brand name, e.g. 'ibuprofen' or 'Advil'"
      },
      "limit": {
       "type": "integer",
       "description": "Max labels [1-10], e.g. 1"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "drug": "ibuprofen",
  "count": 1,
  "cached": false,
  "labels": [
   {
    "warnings": "Allergy alert: Ibuprofen may cause a severe allergic reaction...",
    "brand_name": [
     "Ibuprofen"
    ],
    "generic_name": [
     "IBUPROFEN"
    ],
    "boxed_warning": null,
    "contraindications": null,
    "drug_interactions": "Ask a doctor or pharmacist before use if you are taking aspirin, an anticoagulant...",
    "manufacturer_name": [
     "CVS Pharmacy"
    ],
    "indications_and_usage": "temporarily relieves minor aches and pains..."
   }
  ],
  "source": "openFDA — FDA drug labels (api.fda.gov)",
  "timestamp": "2026-06-24T16:05:00Z",
  "disclaimer": "Indicative data from FDA labels (openFDA), not medical advice."
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/fda-drug-label-lookup-interactions-warnings-contraindications-beb32e4a/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from x402-endpoints.onrender.com](https://www.zero.xyz/host/x402-endpoints.onrender.com/llms.txt)