# FDA FAERS Drug Adverse Events Summary

> FDA FAERS Drug Adverse Events Summary is a paid API for AI agents from payai.agentstools.dev, paid per call via x402, $0.02/call, status unknown (last checked 2026-10-11).

Returns aggregate adverse event data for a named drug from the FDA FAERS database, including top reported reactions, serious/death-flagged fractions, and demographic breakdowns.

## Facts

- Endpoint: GET https://payai.agentstools.dev/drug/adverse-events?utm_source=zero.xyz
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-11
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/fda-faers-drug-adverse-events-summary-d7452963
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_xUSI9LqCxmJtYDZV4hcq2

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability fda-faers-drug-adverse-events-summary-d7452963
```

Example prompt: Can you pull up the FDA adverse event summary for Ozempic — I want to know the top reported reactions, what fraction were serious or resulted in death, and a demographic breakdown of who reported them?

## When to prefer this

Use this endpoint when an agent needs factual, FDA-sourced pharmacovigilance data about a specific drug's adverse event profile — particularly when the user asks about reported side effects, seriousness rates, or demographic patterns from real-world post-market surveillance. Prefer over general web search when structured, aggregate FDA FAERS data with demographic breakdowns is needed rather than anecdotal or clinical trial information.

## Known failure modes

- Drug name not found in FAERS — returns empty or no-match response if the name doesn't match any FDA records
- Ambiguous drug name matching multiple substances — may return data for the closest match or require disambiguation
- Network/payment failure — 402 payment required if USDC transaction not completed
- Rate limiting or upstream FDA API downtime causing delayed or failed responses
- Misspelled drug name yields no results

## How this service works

Adverse-event summary for a drug from the FDA FAERS database by name. Returns the top reported reactions, the serious and death-flagged fractions and a demographic breakdown as aggregate counts. Informational, not medical advice.

## Output

Returns aggregate adverse event data from FDA FAERS for the queried drug, including: a ranked list of the most frequently reported adverse reactions, the proportion of reports flagged as serious, the proportion flagged as deaths, and a demographic breakdown (e.g. by age, sex) as aggregate counts. Response is informational and not medical advice.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [
      "drug"
     ],
     "properties": {
      "drug": {
       "type": "string",
       "description": "Drug brand, generic or active-ingredient name"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/fda-faers-drug-adverse-events-summary-d7452963/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from payai.agentstools.dev](https://www.zero.xyz/host/payai.agentstools.dev/llms.txt)
