# FDA Purple Book Biological Products Lookup

> FDA Purple Book Biological Products Lookup is a paid API for AI agents from api.healthtravel-api.workers.dev, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-29).

Looks up FDA Purple Book licensed biological products by brand name, proper name, or BLA number, returning regulatory details including license type, approval status, biosimilar/interchangeable designation, and exclusivity dates.

## Facts

- Endpoint: GET https://api.healthtravel-api.workers.dev/api/health/fda-purple-book?utm_source=zero.xyz
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-29
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/fda-purple-book-biological-products-lookup-0a6f6f4b
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_1O7TXqIRUuTDWU-iAUxGB

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability fda-purple-book-biological-products-lookup-0a6f6f4b
```

Example prompt: Can you look up adalimumab in the FDA Purple Book and tell me which products are approved biosimilars or interchangeable biologics, including their BLA numbers, applicants, approval dates, and exclusivity expiry dates?

## When to prefer this

Use this endpoint when you need authoritative FDA regulatory data on licensed biological products — especially to determine biosimilar or interchangeable status, BLA number, exclusivity periods, or approval history. Prefer this over general drug databases when the regulatory licensing classification (351(a) vs 351(k)) or Purple Book-specific fields like exclusivity expiry are required.

## Known failure modes

- No results returned if the name or BLA number does not match any Purple Book entry
- Misspelled or unofficial names may return empty results
- Monthly data download may lag real-time FDA approvals by days or weeks
- Limit parameter out of range (e.g. >100) may cause an error or be clamped
- Ambiguous names shared by multiple products may return a large set requiring filtering

## How this service works

FDA Purple Book licensed biological products matching a name (brand or proper name, e.g. adalimumab): applicant, BLA number, license type (351(a) originator, 351(k) biosimilar or interchangeable), strength, dosage form, route, marketing status, approval date, reference product and exclusivity expiry dates, plus the products newly approved or updated this month. From FDA's monthly Purple Book data download.

## Output

Returns a list of matched biological products from the FDA Purple Book, each with fields including applicant name, BLA number, license type (351(a) originator or 351(k) biosimilar/interchangeable), strength, dosage form, route of administration, marketing status, approval date, reference product, and exclusivity expiry dates. Also flags any products newly approved or updated in the current month.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "required": [
      "name"
     ],
     "properties": {
      "name": {
       "type": "string",
       "description": "Brand or proper (nonproprietary) name, or BLA number (required)"
      },
      "limit": {
       "type": "string",
       "description": "Products to return, 1 to 100 (default 25)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/fda-purple-book-biological-products-lookup-0a6f6f4b/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.healthtravel-api.workers.dev](https://www.zero.xyz/host/api.healthtravel-api.workers.dev/llms.txt)