# FLIPI24 24-Month Event Probability Calculator (Maurer 2025)

> FLIPI24 24-Month Event Probability Calculator (Maurer 2025) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Computes 24-month event probability for newly diagnosed follicular lymphoma using the Maurer 2025 FLIPI24 Cox model (Table S5) from age, hemoglobin, WBC, LDH/ULN ratio, and beta-2 microglobulin, with low/intermediate/high risk strata.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/flipi24
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/flipi24-24-month-event-probability-calculator-maurer-2025-54a4c97b
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_veARDM1lcd6-08M2jAktK

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability flipi24-24-month-event-probability-calculator-maurer-2025-54a4c97b
```

Example prompt: Using the Maurer 2025 FLIPI24 model, calculate the 24-month event probability for a 68-year-old follicular lymphoma patient with hemoglobin 11.2 g/dL, WBC 7.4 (10^9/L), LDH/ULN ratio 1.3, and beta-2 microglobulin 3.8 mg/L — and tell me their risk stratum.

## When to prefer this

Use this endpoint when you need the Maurer 2025 FLIPI24 prognostic score specifically — distinct from the original Solal-Céligny FLIPI 2004 — for newly diagnosed follicular lymphoma patients being considered for R-CHOP or bendamustine-rituximab immunochemotherapy. Prefer this over generic FLIPI calculators when the nonlinear age effect (inflection at 75) and beta-2 microglobulin are clinically relevant and lab values are already known.

## Known failure modes

- Missing required query parameter (age, hemoglobin_g_dl, wbc_10e9_l, ldh_uln_ratio, or b2m_mg_l) returns 400 error
- Age outside 18–120 or numeric values outside valid ranges may be rejected or clamped depending on implementation
- Non-integer age value may cause validation error
- Payment not provided or invalid x402 payment header results in 402 Payment Required
- Server-side error returns 500 with no probability output

## How this service works

Maurer 2025 FLIPI24: 24-month event probability in newly diagnosed follicular lymphoma from age (nonlinear, inflection at 75), hemoglobin, WBC, LDH/ULN, and beta-2 microglobulin. Table S5 Cox algorithm assuming R-CHOP or B-R-like immunochemotherapy and 50% anti-CD20 maintenance. Low/intermediate/high at 0.10 and 0.15. Not Solal-Céligny FLIPI 2004. Not a diagnosis or treatment order. magent does not assay labs.

## Output

Returns a 24-month event probability (numeric, 0–1) and a risk stratum classification (low, intermediate, or high) based on the Maurer 2025 Table S5 Cox proportional hazards model, calibrated for patients receiving R-CHOP or bendamustine-rituximab-like immunochemotherapy with ~50% anti-CD20 maintenance. Risk strata use thresholds of 0.10 and 0.15.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "age",
      "hemoglobin_g_dl",
      "wbc_10e9_l",
      "ldh_uln_ratio",
      "b2m_mg_l"
     ],
     "properties": {
      "age": {
       "type": "integer",
       "description": "Age in years (integer 18-120). Maurer 2025 Table S5: no additional age effect 18-60; HR 1.01 per year 60-75 (beta 0.01); HR 1.05 per year 75-90 (extra beta 0.038). Age is clamped to 90 for the linear predictor. magent does not assign age."
      },
      "b2m_mg_l": {
       "type": "number",
       "description": "Beta-2 microglobulin in mg/L (0.1-40). Table S5 linear 1-10 mg/L, HR 1.17 per unit (beta 0.159); values outside 1-10 are clamped. magent does not assay B2M."
      },
      "wbc_10e9_l": {
       "type": "number",
       "description": "White blood cell count in 10^9/L (0.1-80), equal to k/µL. Table S5 linear 4-11, HR 1.08 per unit (beta 0.075); values outside 4-11 are clamped. magent does not assay WBC."
      },
      "ldh_uln_ratio": {
       "type": "number",
       "description": "Caller-assigned serum LDH divided by the local upper limit of normal (0.1-20). Table S5 linear 0.5-5, HR 1.44 per unit (beta 0.364); values outside 0.5-5 are clamped. magent does not measure LDH or set the ULN."
      },
      "hemoglobin_g_dl": {
       "type": "number",
       "description": "Hemoglobin in g/dL (1-25). Table S5 linear 8-17 g/dL, HR 0.92 per unit (beta -0.081); values outside 8-17 are clamped. magent does not assay hemoglobin."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/flipi24-24-month-event-probability-calculator-maurer-2025-54a4c97b/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)