# Glucocorticoid Steroid Dose Converter (Meikle 1977)

> Glucocorticoid Steroid Dose Converter (Meikle 1977) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15).

Converts a glucocorticoid milligram dose between hydrocortisone, prednisone, and dexamethasone using the Meikle 1977 equivalency ratios (20:5:0.75).

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/steroid_conversion
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/glucocorticoid-steroid-dose-converter-meikle-1977-4d7e74b3
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_eA4bd4-AuPwoDxvZHEY8O

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability glucocorticoid-steroid-dose-converter-meikle-1977-4d7e74b3
```

Example prompt: My patient is on 40mg of prednisone daily — what's the equivalent dose in hydrocortisone using standard glucocorticoid equivalency tables?

## When to prefer this

Choose this endpoint when you need a deterministic, citation-backed glucocorticoid dose equivalency calculation among hydrocortisone, prednisone, and dexamethasone. It is ideal for clinical documentation, pharmacy reconciliation, or agent workflows requiring a published reference (Meikle 1977) rather than an LLM estimate. Do not use it for taper schedules, stress-dose protocols, mineralocorticoid equivalency, or steroids outside the three supported drugs.

## Known failure modes

- Invalid 'from' or 'to' steroid name not in the enum (hydrocortisone, prednisone, dexamethasone) returns an error
- dose_mg outside allowed range (0.1–5000 mg) returns a validation error
- Same drug specified for both 'from' and 'to' may return a trivial 1:1 result or an error
- Missing required query parameters returns a 400-level error
- Network or payment failure returns no result

## How this service works

Convert a glucocorticoid milligram dose among hydrocortisone, prednisone, and dexamethasone using Meikle 1977 equivalent doses (20 : 5 : 0.75). Not a taper, stress-dose protocol, or regimen recommendation; mineralocorticoid activity is not converted. Deterministic published table with citation.

## Output

Returns the equivalent dose in the target glucocorticoid in milligrams, calculated using the Meikle 1977 published equivalency ratios (hydrocortisone 20 : prednisone 5 : dexamethasone 0.75), along with the source and target drug names and the authoritative citation.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "from",
      "to",
      "dose_mg"
     ],
     "properties": {
      "to": {
       "enum": [
        "hydrocortisone",
        "prednisone",
        "dexamethasone"
       ],
       "type": "string",
       "description": "Target glucocorticoid. hydrocortisone, prednisone, or dexamethasone (Meikle 1977)."
      },
      "from": {
       "enum": [
        "hydrocortisone",
        "prednisone",
        "dexamethasone"
       ],
       "type": "string",
       "description": "Source glucocorticoid. hydrocortisone, prednisone, or dexamethasone (Meikle 1977)."
      },
      "dose_mg": {
       "type": "number",
       "description": "Dose of the source glucocorticoid in milligrams (0.1-5000)."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "path": "/api/calc/steroid_conversion",
  "count": 2,
  "items": [
   {
    "to": "prednisone",
    "from": "hydrocortisone",
    "dose_mg": 20,
    "formula": "steroid_conversion",
    "citation": {
     "id": "meikle-1977",
     "doi": "10.1016/0002-9343(77)90233-9",
     "title": "Potency and duration of action of glucocorticoids. Effects of hydrocortisone, prednisone and dexamethasone on human pituitary-adrenal function",
     "source": "Am J Med. 1977;63(2):200-207",
     "authors": "Meikle AW, Tyler FH"
    },
    "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
    "to_equivalent_mg": 5,
    "equivalent_dose_mg": 5,
    "formula_expression": "equivalent_dose_mg = dose_mg * (to_equivalent_mg / from_equivalent_mg); hydrocortisone 20 mg = prednisone 5 mg = dexamethasone 0.75 mg (Meikle 1977)",
    "from_equivalent_mg": 20
   },
   {
    "to": "prednisone",
    "from": "hydrocortisone",
    "dose_mg": 20,
    "formula": "steroid_conversion",
    "citation": {
     "id": "meikle-1977",
     "doi": "10.1016/0002-9343(77)90233-9",
     "title": "Potency and duration of action of glucocorticoids. Effects of hydrocortisone, prednisone and dexamethasone on human pituitary-adrenal function",
     "source": "Am J Med. 1977;63(2):200-207",
     "authors": "Meikle AW, Tyler FH"
    },
    "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.",
    "to_equivalent_mg": 5,
    "equivalent_dose_mg": 5,
    "formula_expression": "equivalent_dose_mg = dose_mg * (to_equivalent_mg / from_equivalent_mg); hydrocortisone 20 mg = prednisone 5 mg = dexamethasone 0.75 mg (Meikle 1977)",
    "from_equivalent_mg": 20
   }
  ]
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/glucocorticoid-steroid-dose-converter-meikle-1977-4d7e74b3/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)