# InterPro Entries for UniProt Protein

> InterPro Entries for UniProt Protein is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Returns InterPro family and domain annotations for a given UniProt protein accession

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/interpro-entries-for-protein
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/interpro-entries-for-uniprot-protein-ec5b0d6c
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_rnyIV5mMvNcBuCbzj86RW

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability interpro-entries-for-uniprot-protein-ec5b0d6c -d '<json body>'
```

Example prompt: What InterPro family and domain entries are annotated on the UniProt protein P04637 (human TP53)?

## When to prefer this

Use this endpoint when you need InterPro-specific domain and family annotations for a protein identified by its UniProt accession. Prefer this over general sequence-search tools when you already have a UniProt ID and need structured, pre-computed domain annotation data without running a de novo sequence alignment.

## Known failure modes

- Invalid or non-existent UniProt accession returns empty results or error
- Missing 'acc' query parameter returns a 400 error
- Protein with no InterPro annotations returns an empty entry list
- Network or upstream InterPro database downtime returns 5xx error
- Deprecated or obsolete UniProt accession may yield no results

## How this service works

InterPro family/domain entries annotated on a UniProt protein (param acc, e.g. P04637). Query: ?acc= Returns JSON.

## Output

A JSON object listing all InterPro family and domain entries annotated for the queried UniProt protein, including InterPro entry IDs, names, and classification types (family, domain, homologous superfamily, etc.)

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/interpro-entries-for-uniprot-protein-ec5b0d6c/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)