# IOTA Simple Ultrasound Rules (Timmerman 2008) — M-Rules / B-Rules Classifier

> IOTA Simple Ultrasound Rules (Timmerman 2008) — M-Rules / B-Rules Classifier is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Applies the IOTA simple ultrasound rules (Timmerman 2008) to classify an ovarian mass as malignant, benign, or inconclusive based on five M-rules and five B-rules assigned by the caller.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/iota
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/iota-simple-ultrasound-rules-timmerman-2008-m-rules-b-rules-classifier-e94b876b
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_zDnURPxtVzl1B-m5gG1Ba

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability iota-simple-ultrasound-rules-timmerman-2008-m-rules-b-rules-classifier-e94b876b
```

Example prompt: Apply the IOTA simple ultrasound rules to this ovarian mass: irregular solid tumor = false, ascites = true, at least four papillary structures = false, irregular multilocular solid ≥100mm = false, very high color Doppler = false, unilocular cyst = false, solid component <7mm = false, acoustic shadows = true, smooth multilocular <100mm = false, no detectable blood flow = false — is it malignant, benign, or inconclusive?

## When to prefer this

Choose this endpoint when you need a fast, standardized application of the validated Timmerman 2008 IOTA simple ultrasound rules to caller-assigned ovarian mass features. Prefer it over RMI, Swede score, or SRRisk endpoints when the clinical context specifically calls for the five M-rule / five B-rule binary classification framework. Not appropriate when you need image reading, Doppler measurement, or a continuous malignancy risk score.

## Known failure modes

- Missing required boolean parameter returns a 400-level error
- All flags set to false returns inconclusive (no rules triggered)
- Conflicting M and B rules both true returns inconclusive — caller must verify ultrasound feature assignment
- Endpoint does not interpret ultrasound images; incorrect caller-assigned flags produce incorrect classifications

## How this service works

Timmerman 2008 simple ultrasound rules. Caller assigns five M-rules (irregular solid tumor; ascites; ≥4 papillary structures; irregular multilocular-solid ≥100 mm; very high color Doppler) and five B-rules (unilocular cyst; solid component <7 mm; acoustic shadows; smooth multilocular <100 mm; no Doppler flow). Malignant if any M and no B; benign if any B and no M; otherwise inconclusive. magent does not read ultrasound. Not an ovarian-cancer diagnosis. Not RMI. Not Swede. Not SRRisk.

## Output

Returns a classification of the adnexal mass as malignant (any M-rule true and no B-rule true), benign (any B-rule true and no M-rule true), or inconclusive (neither condition met, or both M and B rules are triggered), based strictly on the five M-rules and five B-rules supplied by the caller.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "irregular_solid_tumor",
      "ascites",
      "at_least_four_papillary_structures",
      "irregular_multilocular_solid_ge_100mm",
      "very_high_color_doppler",
      "unilocular_cyst",
      "solid_component_lt_7mm",
      "acoustic_shadows",
      "smooth_multilocular_lt_100mm",
      "no_detectable_blood_flow"
     ],
     "properties": {
      "ascites": {
       "type": "boolean",
       "description": "Ascites (M-rule). true or false as assigned by the caller. magent does not read ultrasound."
      },
      "unilocular_cyst": {
       "type": "boolean",
       "description": "Unilocular cyst (B-rule). true or false as assigned by the caller. magent does not read ultrasound."
      },
      "acoustic_shadows": {
       "type": "boolean",
       "description": "Acoustic shadows (B-rule). true or false as assigned by the caller. magent does not read ultrasound."
      },
      "irregular_solid_tumor": {
       "type": "boolean",
       "description": "Irregular solid tumor (M-rule). true or false as assigned by the caller (Timmerman 2008). magent does not read ultrasound."
      },
      "solid_component_lt_7mm": {
       "type": "boolean",
       "description": "Solid components with largest solid component <7 mm (B-rule). true or false as assigned by the caller. magent does not measure the mass."
      },
      "very_high_color_doppler": {
       "type": "boolean",
       "description": "Very high color content on color Doppler (M-rule). true or false as assigned by the caller. magent does not perform Doppler."
      },
      "no_detectable_blood_flow": {
       "type": "boolean",
       "description": "No detectable blood flow on Doppler (B-rule). true or false as assigned by the caller. magent does not perform Doppler."
      },
      "smooth_multilocular_lt_100mm": {
       "type": "boolean",
       "description": "Smooth multilocular tumor <100 mm largest diameter (B-rule)
… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/iota-simple-ultrasound-rules-timmerman-2008-m-rules-b-rules-classifier-e94b876b/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)