# Khorana 2008 VTE Risk Score Calculator > Khorana 2008 VTE Risk Score Calculator is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-15). Computes the Khorana 2008 venous thromboembolism (VTE) risk score for cancer patients about to receive chemotherapy, returning a numeric score and low/intermediate/high risk category. ## Facts - Endpoint: GET https://api.magentlab.com/api/calc/khorana - Price: $0.005/call - Payment: x402 - Status: unknown - Last checked: 2026-09-15 - Activations on Zero: 0 - Tags: x402 - Canonical page: https://www.zero.xyz/c/khorana-2008-vte-risk-score-calculator-2262cebe - Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_p85_xazr-yuRPG0d-yIN7 Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently. ## How to call it through Zero Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`): ```sh zero fetch --capability khorana-2008-vte-risk-score-calculator-2262cebe ``` Example prompt: Calculate the Khorana VTE risk score for my patient with pancreatic cancer (very_high site), platelets 380 ×10⁹/L, hemoglobin 9.2 g/dL, WBC 12.5 ×10³/µL, not on ESA, and BMI under 35. ## When to prefer this Use this endpoint when you need to compute the validated Khorana 2008 score specifically — not Padua, Caprini, or other VTE risk tools. Ideal when the caller has already classified cancer site per Khorana categories and has pre-chemotherapy lab values (platelets, hemoglobin, WBC) available. Choose this over a general clinical calculator when you need structured per-criterion point attribution and a machine-readable risk tier for downstream workflow logic. ## Known failure modes - Missing required parameters (cancer_site, platelets_10e9_l, erythropoiesis_stimulating_agent, bmi_ge_35) returns a validation error - Providing both hemoglobin_g_dl and hemoglobin_g_l simultaneously returns an error - Out-of-range values (e.g. platelets outside 1–2000) rejected with range error - Invalid cancer_site string (not 'very_high', 'high', or 'other') causes a parameter error - Providing both wbc_ul and wbc_k_ul simultaneously may cause ambiguity or error ## How this service works Khorana 2008 Blood predictive model for chemotherapy-associated thrombosis: very_high site (stomach or pancreas) 2, high (lung, lymphoma, gynecologic, bladder, testicular) 1, other 0; platelets >=350 1; hemoglobin <10 g/dL or ESA 1 (once); WBC >11 x10^9/L 1; BMI>=35 caller flag 1. Max 6. 0 low; 1-2 intermediate; >=3 high. Not a diagnosis. Not Padua or Caprini. Caller assigns cancer site; magent does not compute BMI. ## Output Returns the total Khorana score (0–6), the risk category (low for 0, intermediate for 1–2, high for ≥3), and a breakdown of points assigned to each criterion (cancer site, platelets, hemoglobin/ESA, WBC, BMI). Does not make diagnostic or treatment decisions. ## Request schema (JSON Schema) ```json { "type": "object", "$schema": "https://json-schema.org/draft/2020-12/schema", "required": [ "input" ], "properties": { "input": { "type": "object", "required": [ "type", "method" ], "properties": { "type": { "type": "string", "const": "http" }, "method": { "enum": [ "GET", "HEAD", "DELETE" ], "type": "string" }, "headers": { "type": "object", "additionalProperties": { "type": "string" } }, "queryParams": { "type": "object", "required": [ "cancer_site", "platelets_10e9_l", "erythropoiesis_stimulating_agent", "bmi_ge_35" ], "properties": { "wbc_ul": { "type": "number", "description": "WBC in cells/µL (same as cells/mm^3). Provide wbc_k_ul or wbc_ul. Range 10-500000. >11000 scores 1 (11000 does not)." }, "wbc_k_ul": { "type": "number", "description": "WBC in 10^3/µL (same as 10^9/L). Provide wbc_k_ul or wbc_ul. Range 0.01-500. >11 scores 1 (11.0 does not)." }, "bmi_ge_35": { "type": "boolean", "description": "BMI ≥35 as assigned by the caller. true or false. magent does not take height or weight. 1 point if true." }, "cancer_site": { "type": "string", "description": "Caller-assigned Khorana site class. very_high (stomach or pancreas) scores 2; high (lung, lymphoma, gynecologic, bladder, or testicular) scores 1; other scores 0. magent does not assign cancer site from histology text." }, "hemoglobin_g_l": { "type": "number", "description": "Hemoglobin in g/L (30-220). Converted as hemoglobin_g_dl = hemoglobin_g_l / 10. Provide this or hemoglobin_g_dl, not both." }, "hemoglobin_g_dl": { "type": "number", "description": "Hemoglobin in g/dL (3-22). Provide this or hemoglobin_g_l, not both. <10 scores 1 with ESA (once, not twice). 10.0 does not score unless ESA is true." }, "platelets_10e9_l": { "type": "number", "description": "Pre-chemotherapy platelet count ×10^9/L (1-2000). ≥350 scores 1 (350 scores; 349 does not)." }, "erythropoiesis_stimulating_agent": { "type": "boolean", "description": "Use of an erythropoiesis-stimulating agent as assigned by the caller. true or false. Scores 1 with hemoglobin <10 g/dL (once, not twice)." } } } }, "additionalProperties": false }, "output … (truncated) ``` ## Response schema (JSON Schema) ```json { "type": "json", "example": { "path": "/api/calc/khorana", "count": 2, "items": [ { "score": 0, "wbc_ul": 8000, "formula": "khorana", "citation": { "id": "khorana-2008", "doi": "10.1182/blood-2007-10-116327", "title": "Development and validation of a predictive model for chemotherapy-associated thrombosis", "source": "Blood. 2008;111(10):4902-4907", "authors": "Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW" }, "bmi_ge_35": false, "max_score": 6, "components": [ { "value": "other", "factor": "cancer_site", "points": 0, "present": false }, { "value": 200, "factor": "platelets", "points": 0, "present": false }, { "value": { "hemoglobin_g_dl": 12, "erythropoiesis_stimulating_agent": false }, "factor": "hemoglobin_or_esa", "points": 0, "present": false }, { "value": 8000, "factor": "wbc", "points": 0, "present": false }, { "factor": "bmi_ge_35", "points": 0, "present": false } ], "disclaimer": "Not a medical device. Deterministic published-formula or published-code output for autonomous agents. A licensed clinician remains responsible for patient care and billing submissions.", "cancer_site": "other", "khorana_risk": "low", "hemoglobin_g_dl": 12, "platelets_10e9_l": 200, "formula_expression": "Khorana = cancer_site (very_high 2, high 1, other 0) + (platelets>=350) + (hemoglobin<10 g/dL or ESA) + (wbc>11 x10^9/L) + (BMI>=35); max 6; 0 low, 1-2 intermediate, >=3 high", "erythropoiesis_stimulating_agent": false }, { "score": 0, "wbc_ul": 8000, "formula": "khorana", "citation": { "id": "khorana-2008", "doi": "10.1182/blood-2007-10-116327", "title": "Development and validation of a predictive model for chemotherapy-associated thrombosis", "source": "Blood. 2008;111(10):4902-4907", "authors": "Khorana AA, Kuderer NM, Culakova E, Lyman GH, Francis CW" }, "bmi_ge_35": false, "max_score": 6, "components": [ { "value": "other", "factor": "cancer_site", "points": 0, "present": false }, { "value": 200, "factor": "platelets", "points": 0, "present": false }, { "value": { "hemoglobin_g_dl": 12, "erythropoiesis_stimulating_agent": f … (truncated) ``` ## More - Live health (JSON, refreshed every minute): https://www.zero.xyz/c/khorana-2008-vte-risk-score-calculator-2262cebe/health.json - [Zero catalog index](https://www.zero.xyz/llms.txt) - [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)