# LongevityPulse Clinical Trial Finder

> LongevityPulse Clinical Trial Finder is a paid API for AI agents from longevitypulse.theaslangroupllc.com, paid per call via x402, $0.1/call, status unknown (last checked 2026-09-16).

Searches ClinicalTrials.gov for active longevity and anti-aging clinical trials by condition, intervention (rapamycin, metformin, NMN, senolytics, caloric restriction), or location worldwide, returning eligibility criteria and application instructions.

## Facts

- Endpoint: GET https://longevitypulse.theaslangroupllc.com/api/longevity/clinical-trials
- Price: $0.1/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-16
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/longevitypulse-clinical-trial-finder-1120ac33
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_6iYjJwS3CTgdBdrC21wEt

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability longevitypulse-clinical-trial-finder-1120ac33
```

Example prompt: Can you find active clinical trials studying rapamycin for longevity or anti-aging in the United States that are currently recruiting — I want to know if I'm eligible and how to apply?

## When to prefer this

Use this endpoint when a user wants to discover enrolling longevity or anti-aging clinical trials, especially for specific geroprotective interventions like rapamycin, metformin, NMN, senolytics, or caloric restriction. Prefer over a generic ClinicalTrials.gov search when the query is specifically longevity/healthspan-focused and you want curated, eligibility-annotated results with application guidance.

## Known failure modes

- No trials found for the specified condition or intervention — returns empty result set
- Invalid or unrecognized intervention name — may return empty or broad results
- Location too specific with no nearby trials — returns empty or geographically expanded results
- ClinicalTrials.gov upstream API unavailable — returns 503 or error message
- Payment not processed (x402) — request blocked before reaching the API

## How this service works

Global longevity intelligence API — biomarker interpretation, supplement evidence, personalized protocols, clinical trials, Blue Zone research, WHO country longevity…

## Output

A list of active longevity/anti-aging clinical trials sourced from ClinicalTrials.gov, including trial name, NCT ID, status, intervention type, eligibility criteria, enrollment details, sponsor, location(s), and instructions on how to apply or contact the study team.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "lang": {
       "type": "string",
       "description": "en | es | fr | de | ja | zh | ko | pt | ar | hi (default: en)"
      },
      "condition": {
       "type": "string",
       "description": "Condition or intervention to search — e.g. \"aging\" | \"rapamycin\" | \"metformin\" | \"NMN\" | \"senolytics\" | \"caloric restriction\" | \"longevity\" | \"Alzheimer prevention\""
      },
      "max_trials": {
       "type": "string",
       "description": "Trials to return, 1-20 (default 10). Pay-per-trial via the upto scheme: $0.04 + $0.003/trial (10 trials = $0.07); exact-scheme payments are flat $0.10."
      },
      "recruiting_only": {
       "type": "string",
       "description": "\"true\" to show only actively recruiting trials (default: true)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "errors": {
     "type": "object",
     "description": "Documented error responses, keyed by HTTP status code",
     "additionalProperties": {
      "type": "object",
      "required": [
       "description"
      ],
      "properties": {
       "example": {
        "type": "object"
       },
       "description": {
        "type": "string"
       }
      }
     }
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "trials": [
   {
    "phase": "Phase 2",
    "title": "PEARL Trial: Rapamycin for Healthy Aging",
    "nct_id": "NCT05483452",
    "status": "RECRUITING",
    "intervention": "Rapamycin 5mg weekly",
    "why_it_matters": "First major human RCT of rapamycin for longevity in healthy adults — results could transform longevity medicine"
   }
  ],
  "search_summary": {
   "total_found": 8,
   "global_scope": "US, UK, Australia, Canada, Israel",
   "recruiting_now": 5,
   "condition_searched": "rapamycin"
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/longevitypulse-clinical-trial-finder-1120ac33/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from longevitypulse.theaslangroupllc.com](https://www.zero.xyz/host/longevitypulse.theaslangroupllc.com/llms.txt)