# LongevityPulse Supplement Intelligence

> LongevityPulse Supplement Intelligence is a paid API for AI agents from longevitypulse.vercel.app, paid per call via x402, $0.2/call, status unknown (last checked 2026-09-15).

Returns evidence-graded analysis of longevity supplements (NMN, NR, berberine, spermidine, urolithin A, fisetin, resveratrol, and 50+ more), distinguishing human RCT evidence from animal studies and including global availability data.

## Facts

- Endpoint: GET https://longevitypulse.vercel.app/api/longevity/supplement-intel
- Price: $0.2/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/longevitypulse-supplement-intelligence-c606d3ac
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_PzezAF09LdEb0QeukPRmA

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability longevitypulse-supplement-intelligence-c606d3ac
```

Example prompt: Give me a full evidence-graded breakdown of NMN as a longevity supplement — I want to know what the human RCTs actually show versus just animal studies, and whether it's available where I live.

## When to prefer this

Use this endpoint when an agent or user needs rigorous, evidence-tiered analysis of a specific longevity or wellness supplement — especially when distinguishing human RCT evidence from animal-only data matters. Prefer this over generic supplement databases when the use case is longevity-focused and evidence quality grading is required.

## Known failure modes

- Unknown or unsupported supplement name returns an error or empty result
- Supplement not yet in the database of 50+ compounds
- Network timeout from Vercel serverless cold start
- Payment not processed correctly via x402 protocol resulting in 402 error
- Ambiguous compound name (e.g. generic term) may return unexpected result

## How this service works

Supplement intelligence (NMN, NR/NAD+, berberine, spermidine, urolithin A, fisetin, resveratrol, creatine) for longevity and wellness agents. Evidence-graded analysis of any longevity compound, 50+ in all, with human-RCT-vs-animal evidence and global availability. Health intelligence, not medical advice.

## Output

A structured evidence-graded profile of the requested longevity supplement, including a grading of the quality of evidence (distinguishing human RCTs from animal studies), mechanism of action, dosage guidance, and global availability information.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "lang": {
       "type": "string",
       "description": "en | es | fr | de | ja | zh | ko | pt | ar | hi (default: en)"
      },
      "region": {
       "type": "string",
       "description": "Optional audience region/country (e.g. \"UK\") — surfaces region-specific supplement retailers"
      },
      "compound": {
       "type": "string",
       "description": "Compound name — e.g. \"NMN\" | \"NR\" | \"berberine\" | \"spermidine\" | \"urolithin A\" | \"fisetin\" | \"quercetin\" | \"alpha-ketoglutarate\" | \"resveratrol\" | \"taurine\" | \"NAD+\""
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "errors": {
     "type": "object",
     "description": "Documented error responses, keyed by HTTP status code",
     "additionalProperties": {
      "type": "object",
      "required": [
       "description"
      ],
      "properties": {
       "example": {
        "type": "object"
       },
       "description": {
        "type": "string"
       }
      }
     }
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "category": "NAD+ precursor",
  "compound": "NMN (Nicotinamide Mononucleotide)",
  "evidence_summary": {
   "human_rct_evidence": "3 small RCTs showing NAD+ elevation in humans; limited outcome data",
   "overall_evidence_grade": "Moderate — strong animal data, limited human RCTs, promising early human results"
  },
  "primary_mechanism": "Raises intracellular NAD+ levels, activating SIRT1/3 and PARP1 — key enzymes in DNA repair, mitochondrial biogenesis, and metabolic regulation",
  "global_availability": {
   "regulatory_status": "OTC dietary supplement in US, UK, EU, Australia, Canada, Singapore; limited availability in some Asian markets"
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/longevitypulse-supplement-intelligence-c606d3ac/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from longevitypulse.vercel.app](https://www.zero.xyz/host/longevitypulse.vercel.app/llms.txt)