# Monarch Initiative Entity Search

> Monarch Initiative Entity Search is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-15).

Search the Monarch Initiative biomedical knowledge graph for diseases, genes, and phenotypes by a free-text query string

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/monarch-entity-search
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/monarch-initiative-entity-search-53d73914
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_niJOW106Y2huXNDixUBwi

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability monarch-initiative-entity-search-53d73914 -d '<json body>'
```

Example prompt: Can you search the Monarch Initiative knowledge graph for 'Marfan syndrome' and show me what diseases, genes, and phenotypes come up?

## When to prefer this

Choose this endpoint when you need to look up biomedical entities — diseases, genes, or phenotypes — from the authoritative Monarch Initiative knowledge graph. Ideal for rare disease research, bioinformatics workflows, or any use case requiring structured biomedical entity search with standardized identifiers. Prefer this over generic web search when you need structured, ontology-backed biomedical data.

## Known failure modes

- Empty query string returns no results or an error
- Misspelled disease or gene names may return zero matches
- Rare or obscure terms may return sparse results
- Network timeout or service unavailability returns an HTTP error
- Query too broad may return too many low-relevance results

## How this service works

Search the Monarch Initiative knowledge graph for diseases, genes and phenotypes by query {q}. Query: ?q= Returns JSON.

## Output

A JSON response containing matched biomedical entities from the Monarch Initiative knowledge graph, including diseases, genes, and phenotype terms relevant to the search query, along with identifiers and descriptive metadata for each match.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/monarch-initiative-entity-search-53d73914/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)