# Motzer 1999 MSKCC RCC Prognostic Score

> Motzer 1999 MSKCC RCC Prognostic Score is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Calculates the Motzer 1999 MSKCC prognostic score for metastatic renal cell carcinoma using five binary risk factors, yielding a risk group of favorable, intermediate, or poor.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/motzer
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/motzer-1999-mskcc-rcc-prognostic-score-7b67cc35
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_8W72GdZdayko08YzFQuiy

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability motzer-1999-mskcc-rcc-prognostic-score-7b67cc35
```

Example prompt: Calculate the Motzer 1999 MSKCC prognostic score for a metastatic RCC patient who has KPS below 80, LDH above 1.5 times the upper limit of normal, hemoglobin below the lower limit of normal, corrected calcium above 10 mg/dL, and has not had a prior nephrectomy.

## When to prefer this

Use this endpoint when you need the original cytokine-era Motzer 1999 MSKCC five-factor prognostic model specifically (KPS, LDH, hemoglobin, corrected calcium, nephrectomy status). Prefer this over the IMDC/Heng 2009 endpoint when the clinical context calls for the historical Motzer 1999 criteria — e.g., cytokine-era trial comparisons or when the ordering clinician specifies the 1999 MSKCC model. Do not use this for IMDC risk stratification used in contemporary immunotherapy trials.

## Known failure modes

- Missing any of the five required boolean parameters returns a validation error
- Passing non-boolean values for the risk factor fields causes a schema rejection
- Confusing this with the IMDC (Heng 2009) model may yield incorrect risk stratification for immunotherapy-era patients
- Confusing with Motzer 2002 or 2004 variants may cause misclassification if criteria differ

## How this service works

Motzer 1999 MSKCC: KPS <80, LDH >1.5×ULN, hemoglobin <LLN, corrected calcium >10 mg/dL, no prior nephrectomy; 1 point each, max 5. Favorable 0, intermediate 1–2, poor ≥3. Deterministic published score with citation; not an RCC diagnosis or treatment recommendation; not IMDC; not Motzer 2002/2004. magent does not assign KPS or assay LDH, hemoglobin, or calcium.

## Output

Returns the total Motzer 1999 MSKCC score (0–5, one point per positive risk factor) and the corresponding risk group: favorable (0 points), intermediate (1–2 points), or poor (≥3 points), along with a citation to the original Motzer 1999 publication. Does not return a diagnosis, treatment recommendation, or IMDC classification.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "kps_lt_80",
      "ldh_gt_1_5_uln",
      "hemoglobin_lt_lln",
      "corrected_calcium_gt_10",
      "no_prior_nephrectomy"
     ],
     "properties": {
      "kps_lt_80": {
       "type": "boolean",
       "description": "Karnofsky performance status <80% as assigned by the caller (Motzer 1999). true scores 1. magent does not observe KPS."
      },
      "ldh_gt_1_5_uln": {
       "type": "boolean",
       "description": "Serum LDH >1.5 × institutional ULN as assigned by the caller (Motzer 1999). true scores 1. magent does not assay LDH or apply ULN."
      },
      "hemoglobin_lt_lln": {
       "type": "boolean",
       "description": "Hemoglobin below the institutional lower limit of normal as assigned by the caller (Motzer 1999). true scores 1. magent does not assay hemoglobin or apply LLN."
      },
      "no_prior_nephrectomy": {
       "type": "boolean",
       "description": "Absence of prior nephrectomy as assigned by the caller (Motzer 1999). true scores 1. Not Motzer 2004 time from diagnosis to treatment. magent does not review operative history."
      },
      "corrected_calcium_gt_10": {
       "type": "boolean",
       "description": "Corrected calcium >10 mg/dL as assigned by the caller (Motzer 1999 paper threshold, not institutional ULN). true scores 1. magent does not assay calcium."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/motzer-1999-mskcc-rcc-prognostic-score-7b67cc35/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)