# NCBI dbSNP Variant Search via E-utilities

> NCBI dbSNP Variant Search via E-utilities is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-15).

Searches NCBI dbSNP and returns matching variant UIDs for a given query string using the NCBI E-utilities API.

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/ncbi-esearch-dbsnp
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/ncbi-dbsnp-variant-search-via-e-utilities-1a702e44
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_2v3j_ij7h4zzhmfCrTtfd

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability ncbi-dbsnp-variant-search-via-e-utilities-1a702e44 -d '<json body>'
```

Example prompt: Search NCBI dbSNP for all variant records matching 'BRCA1 pathogenic' and give me the UIDs.

## When to prefer this

Use this endpoint when you need to programmatically search NCBI dbSNP for variant UIDs by keyword, gene name, rs number, or phenotype — especially when integrating with downstream NCBI E-utilities (e.g., EFetch) in a bioinformatics pipeline. Prefer this over manual NCBI web searches when automation is required.

## Known failure modes

- Empty result set if query matches no dbSNP records
- NCBI E-utilities rate limiting or service unavailability returning an error
- Malformed query string producing zero results or unexpected output
- Payment failure returning HTTP 402 before any NCBI call is made

## How this service works

Search NCBI dbSNP and return matching variant UIDs for query {q} via E-utilities. Query: ?q= Returns JSON.

## Output

A JSON object containing a list of dbSNP variant UIDs (esearchresult) matching the query, including count, query key, web environment, and an array of UIDs — suitable for downstream NCBI E-utilities fetches.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/ncbi-dbsnp-variant-search-via-e-utilities-1a702e44/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)