# NCBI Nucleotide (GenBank) E-Search via clonecho

> NCBI Nucleotide (GenBank) E-Search via clonecho is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Searches the NCBI Nucleotide (GenBank) database and returns matching UIDs for a given query using NCBI E-utilities.

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/ncbi-esearch-nuccore
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/ncbi-nucleotide-genbank-e-search-via-clonecho-59a606d2
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_JU9XpPM0jpE6Ki5txW3MQ

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability ncbi-nucleotide-genbank-e-search-via-clonecho-59a606d2 -d '<json body>'
```

Example prompt: Search GenBank's nucleotide database for sequences matching 'BRCA1 homo sapiens' and give me the matching UIDs I can use to fetch the actual records.

## When to prefer this

Use this endpoint when you need to discover NCBI Nucleotide / GenBank record UIDs for a biological query (gene, organism, accession, keyword) as a first step before fetching full sequence records. Prefer this over direct NCBI API calls when you need a simple, paid-per-call REST interface without managing NCBI API keys or rate limits.

## Known failure modes

- Empty result set if no nucleotide records match the query
- Malformed or overly broad query returning too many UIDs
- NCBI E-utilities rate limiting or downtime causing failure
- Invalid query syntax returning an error response
- Network timeout if NCBI backend is slow to respond

## How this service works

Search NCBI Nucleotide (GenBank) and return matching UIDs for query {q} via E-utilities. Query: ?q= Returns JSON.

## Output

A JSON object containing a list of NCBI Nucleotide UIDs (numeric identifiers) matching the search query, which can then be used to fetch full sequence records from GenBank via other E-utility endpoints.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/ncbi-nucleotide-genbank-e-search-via-clonecho-59a606d2/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)