# NCBI SRA E-Search

> NCBI SRA E-Search is a paid API for AI agents from clonecho.builda.company, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-14).

Searches the NCBI Sequence Read Archive (SRA) using NCBI E-utilities and returns matching UIDs for a given query string.

## Facts

- Endpoint: POST https://clonecho.builda.company/x402/s/ncbi-esearch-sra
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/ncbi-sra-e-search-b5d07866
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_-Q_ntKeJlzNgZH7ZeG48s

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability ncbi-sra-e-search-b5d07866 -d '<json body>'
```

Example prompt: Search the NCBI Sequence Read Archive for all datasets related to 'Homo sapiens RNA-seq' and give me the matching UIDs.

## When to prefer this

Use this endpoint when you need to programmatically search the NCBI Sequence Read Archive (SRA) for sequencing datasets by keyword, organism, experiment type, or other biological terms, and retrieve the corresponding SRA UIDs for downstream processing. Prefer this over manual NCBI web searches when building automated bioinformatics pipelines or data retrieval workflows.

## Known failure modes

- Empty result set if no SRA records match the query term
- Invalid or malformed query string may return an error or zero results
- NCBI E-utilities rate limits or downtime could cause failures
- Very broad queries may return truncated result sets due to NCBI limits
- Network or upstream NCBI API errors returning non-200 status

## How this service works

Search the NCBI Sequence Read Archive and return matching UIDs for query {q} via E-utilities. Query: ?q= Returns JSON.

## Output

A JSON object containing a list of NCBI SRA UIDs (numeric identifiers) that match the given query, returned via NCBI E-utilities esearch against the SRA database.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/ncbi-sra-e-search-b5d07866/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from clonecho.builda.company](https://www.zero.xyz/host/clonecho.builda.company/llms.txt)