# OIX TrialScout Rare Disease Clinical Trial Market Report

> OIX TrialScout Rare Disease Clinical Trial Market Report is a paid API for AI agents from oix-autonomous-economy.fly.dev, paid per call via x402, $0.25/call, status down (last checked 2026-09-16).

Returns monitored clinical trial observations and evidence scores for the rare-disease trials market, sourced from ClinicalTrials.gov and similar primary sources.

## Facts

- Endpoint: GET https://oix-autonomous-economy.fly.dev/api/x402/portfolio/trialscout-rare
- Price: $0.25/call
- Payment: x402
- Status: down
- Last checked: 2026-09-16
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/oix-trialscout-rare-disease-clinical-trial-market-report-96bb9e5d
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_IhSewdj9AmbmGsNKsDoe1

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability oix-trialscout-rare-disease-clinical-trial-market-report-96bb9e5d
```

Example prompt: Can you pull the latest rare disease clinical trial market report from TrialScout — show me the top 10 observations with an evidence score of at least 70, focused on orphan drug trials?

## When to prefer this

Choose this endpoint when you need evidence-scored, primary-source clinical trial intelligence specifically for the rare disease market, with on-chain settlement proof and source digests for auditability. Prefer it over generic web searches when you need structured, machine-readable trial observations with quantified evidence scores and provenance hashes, especially for vendor prospecting or site identification workflows.

## Known failure modes

- Payment not provided or insufficient USDC — returns 402 Payment Required
- Invalid minScore value outside 0-100 range — returns 400 Bad Request
- Query string exceeds 120 characters — returns 400 Bad Request
- limit parameter outside 1-25 range — returns 400 Bad Request
- Upstream ClinicalTrials.gov source unavailable — may return stale or empty observations
- Asset slug not found — returns 404 Not Found

## How this service works

Package any earning logic as an autonomous asset. OIX provides identity, runtime, capital policy, ownership, proof, settlement, and exchange infrastructure.

## Output

A JSON object containing: the asset name and market slug ('trialscout-rare'), a product offer description with price and settlement info, an array of up to 25 clinical trial observations each with a URL, OIX evidence score (0-100), title, and evidence details, plus the total number of monitored records, SHA-256 report and source digests for proof, and protocol version (oix.machine-report/v1).

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "q": {
       "type": "string",
       "maxLength": 120,
       "description": "Optional term matched against the current source-backed observations."
      },
      "limit": {
       "type": "integer",
       "default": 25,
       "maximum": 25,
       "minimum": 1,
       "description": "Maximum observations returned."
      },
      "minScore": {
       "type": "integer",
       "default": 0,
       "maximum": 100,
       "minimum": 0,
       "description": "Minimum OIX evidence score."
      }
     },
     "additionalProperties": false
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "asset": {
   "name": "TrialScout Rare Disease",
   "slug": "trialscout-rare",
   "market": "Rare-disease trials"
  },
  "proof": {
   "reportDigest": "sha256:…",
   "sourceDigest": "sha256:…"
  },
  "product": {
   "offer": "Clinical-trial sponsor and site report",
   "price": "0.25 USDC",
   "settlement": "x402 · Base mainnet"
  },
  "decision": {
   "buyer": "Rare-disease research vendors",
   "observations": [
    {
     "url": "https://clinicaltrials.gov/data-about-studies/learn-about-api",
     "score": 90,
     "title": "Primary-source market signal",
     "evidence": {}
    }
   ],
   "monitoredRecords": 40,
   "returnedObservations": 25
  },
  "protocol": "oix.machine-report/v1"
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/oix-trialscout-rare-disease-clinical-trial-market-report-96bb9e5d/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from oix-autonomous-economy.fly.dev](https://www.zero.xyz/host/oix-autonomous-economy.fly.dev/llms.txt)