# Pardanani 2018 MAPS Hybrid Prognostic Score for Systemic Mastocytosis

> Pardanani 2018 MAPS Hybrid Prognostic Score for Systemic Mastocytosis is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Calculates the Pardanani 2018 MAPS hybrid clinical-molecular prognostic score (Figure 3) for systemic mastocytosis, returning a numeric score and risk tier (Low/Intermediate-1/Intermediate-2/High).

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/maps
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/pardanani-2018-maps-hybrid-prognostic-score-for-systemic-mastocytosis-c8278e04
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_g-ssbAMYskZL_dRZvYdCO

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability pardanani-2018-maps-hybrid-prognostic-score-for-systemic-mastocytosis-c8278e04
```

Example prompt: Calculate the Pardanani 2018 MAPS hybrid score for a 68-year-old patient with advanced SM (ASM), platelets of 110×10^9/L, alkaline phosphatase above the upper normal limit, and a confirmed ASXL1 mutation.

## When to prefer this

Use this endpoint when you need to apply the Pardanani 2018 MAPS hybrid clinical-molecular prognostic model (Figure 3) specifically — combining SM category, age, platelet count, ALP status, and ASXL1/RUNX1/NRAS mutation status. Prefer this over clinical-only or WHO/ICC-criteria-based tools when the hybrid score is explicitly required. Note: this endpoint does not perform sequencing, platelet counting, or ALP assay — callers must supply pre-determined values.

## Known failure modes

- Invalid sm_category token (not 'indolent' or 'advanced') returns invalid_maps error
- Age outside 18-120 range causes validation failure
- Platelet count outside 1-2000 range causes validation failure
- Missing required query parameters returns 400-level error
- Caller-supplied clinical data that is inconsistent (e.g. platelets=0) may cause rejection

## How this service works

Pardanani 2018 MAPS hybrid clinical-molecular (Figure 3): advanced SM 2 (ASM, SM-AHN, or MCL; ISM/SSM 0), age >60 1, platelets <150×10^9/L 1, ALP above UNL 1, ASXL1/RUNX1/NRAS 1; max 6. Low ≤2, intermediate-1 3, intermediate-2 4, high ≥5. Not WHO SM, not ICC SM, not clinical-only Figure 1. magent does not sequence, assay ALP, or count platelets.

## Output

Returns the computed MAPS total score (integer 0-6), the corresponding risk tier label (Low ≤2, Intermediate-1 = 3, Intermediate-2 = 4, High ≥5), and per-variable point contributions based on Pardanani 2018 Figure 3.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "sm_category",
      "age",
      "platelets_10e9_l",
      "alp_above_unl",
      "adverse_mutations"
     ],
     "properties": {
      "age": {
       "type": "integer",
       "description": "Age in years (18-120, Params.age). >60 scores 1 (Pardanani 2018 Figure 3). 60 is the ≤60 arm and scores 0."
      },
      "sm_category": {
       "type": "string",
       "description": "Caller-assigned SM category for Pardanani 2018 hybrid Figure 3. indolent (ISM/SSM) scores 0. advanced (ASM, SM-AHN, or MCL) scores 2. Other tokens are invalid_maps. Not WHO SM criteria. magent does not assign WHO or ICC SM."
      },
      "alp_above_unl": {
       "type": "boolean",
       "description": "Serum alkaline phosphatase above the upper normal limit as assigned by the caller (Pardanani 2018 Figure 3). true scores 1. magent does not assay ALP."
      },
      "platelets_10e9_l": {
       "type": "number",
       "description": "Platelet count in 10^9/L (1-2000). <150 scores 1 (Pardanani 2018 Figure 3). 150.0 is the ≥150 arm and scores 0. magent does not assay platelets."
      },
      "adverse_mutations": {
       "type": "boolean",
       "description": "ASXL1, RUNX1, or NRAS as assigned by the caller (Pardanani 2018 hybrid Figure 3). true scores 1. magent does not sequence."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/pardanani-2018-maps-hybrid-prognostic-score-for-systemic-mastocytosis-c8278e04/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)