# PatentPulse Pharma Patent Cliff Analysis

> PatentPulse Pharma Patent Cliff Analysis is a paid API for AI agents from patentpulse-self.vercel.app, paid per call via x402, $0.15/call, status unknown (last checked 2026-09-15).

Returns a drug patent expiry calendar and generic-entry analysis for pharma patent cliff intelligence.

## Facts

- Endpoint: GET https://patentpulse-self.vercel.app/api/patent/cliff
- Price: $0.15/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/patentpulse-pharma-patent-cliff-analysis-91bc2550
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_3_IUFjNd_dcsOfq_Ox8pn

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability patentpulse-pharma-patent-cliff-analysis-91bc2550
```

Example prompt: Pull the patent cliff analysis for top-selling GLP-1 drugs like Ozempic and Wegovy — I need the expiry calendar and generic entry windows over the next 5 years for an investment memo.

## When to prefer this

Use this endpoint when you need pharma-specific patent cliff intelligence — expiry calendars, generic entry timelines, and exclusivity windows — for IP strategy, investment analysis, or business development decisions in the pharmaceutical space. Prefer this over general patent search endpoints when the core question is about when a drug loses protection and generic competition begins.

## Known failure modes

- Drug or compound not found in patent database — returns empty result or 404
- Invalid query parameters — returns 400 with parameter validation error
- Patent data temporarily unavailable for a jurisdiction — partial result with warning
- Payment not processed — returns 402 payment required
- Rate limit exceeded — returns 429 with retry-after header

## How this service works

Pharma patent cliff / drug patent expiry / generic-entry analysis by drug name (e.g. Humira, Ozempic). Returns the patent expiry calendar, exclusivity timeline, and generic/biosimilar entry outlook across US, EU, and Japan, plus related USPTO patents. For IP and investment agents. Worldwide.

## Output

Returns a structured patent expiry calendar including drug names, patent expiration dates, exclusivity end dates, generic entry timelines, and revenue-at-risk indicators for specified drugs or therapeutic categories.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "required": [
  "drug"
 ],
 "properties": {
  "drug": {
   "type": "string",
   "description": "Drug name — generic or brand (e.g. humira, ozempic, keytruda)"
  },
  "lang": {
   "type": "string",
   "description": "Response language"
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {}
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/patentpulse-pharma-patent-cliff-analysis-91bc2550/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from patentpulse-self.vercel.app](https://www.zero.xyz/host/patentpulse-self.vercel.app/llms.txt)