# Pharma Regulatory Compliance Digest (LLM Brief)

> Pharma Regulatory Compliance Digest (LLM Brief) is a paid API for AI agents from oracles-production.up.railway.app, paid per call via x402, $0.25/call, status unknown (last checked 2026-09-15).

Returns an LLM-generated summary of the most important prescription drug and biologics regulatory compliance rules and deadlines from a recent time window.

## Facts

- Endpoint: GET https://oracles-production.up.railway.app/v1/reg-pharma/brief
- Price: $0.25/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-15
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/pharma-regulatory-compliance-digest-llm-brief-9a1d0b55
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_oJFztRQE0lHdRkGZXculo

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability pharma-regulatory-compliance-digest-llm-brief-9a1d0b55
```

Example prompt: Give me a quick LLM-written compliance brief on any prescription drug or biologics regulatory rules and deadlines that have come up in the last 30 days — just the stuff that actually matters.

## When to prefer this

Use this endpoint when you need a human-readable, LLM-curated summary of pharma compliance obligations rather than raw regulatory data. Ideal for compliance officers, legal teams, or agents that need to surface only the most actionable drug and biologics rules from recent regulatory activity without sifting through raw filings. Prefer this over raw EDGAR or FDA data feeds when the user needs narrative context and deadline callouts rather than structured records.

## Known failure modes

- No regulatory changes found in the specified window — may return empty brief or low basedOnChanges count
- Invalid 'since' datetime format causes 400 error
- LLM generation failure may fall back to template-generated output (generatedBy: 'template')
- Payment not processed (x402 payment required) results in 402 error
- Window too large may result in degraded or truncated brief

## How this service works

LLM-written compliance digest of the prescription drugs & biologics rules in the window that actually matter (drug, biologic, nda, anda, clinical) — issuing agency named, deadlines called out.

## Output

Returns a JSON object containing a 'brief' field with an LLM-generated plain-language summary of the most significant pharmaceutical and biologics compliance rules and deadlines in the requested window, a 'generatedBy' field indicating whether the summary came from an LLM or a template, and 'basedOnChanges' indicating how many underlying regulatory changes were analyzed.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "since": {
       "type": "string",
       "format": "date-time",
       "description": "Window start (default: last 30 days)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object",
     "properties": {
      "brief": {
       "type": "string"
      },
      "generatedBy": {
       "enum": [
        "llm",
        "template"
       ],
       "type": "string"
      },
      "basedOnChanges": {
       "type": "integer"
      }
     }
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/pharma-regulatory-compliance-digest-llm-brief-9a1d0b55/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from oracles-production.up.railway.app](https://www.zero.xyz/host/oracles-production.up.railway.app/llms.txt)