# Pocket Network Pharma Signals – FDA & Drug Market Safety Briefs

> Pocket Network Pharma Signals – FDA & Drug Market Safety Briefs is a paid API for AI agents from agent.pocket.network, paid per call via x402, $0.005/call, status unknown (last checked 2026-10-16).

Returns scored (0-100) safety and market intelligence briefs for US pharma verticals and specific drug makers (Pfizer, Lilly, J&J), sourced from openFDA, FDA, BLS, and ClinicalTrials.gov

## Facts

- Endpoint: POST https://agent.pocket.network/v1/pmic-pharma-signals?utm_source=zero.xyz
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-16
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/pocket-network-pharma-signals-fda-drug-market-safety-briefs-4ff61185
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_-geueNV2mCfWE3T0IFqkB

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability pocket-network-pharma-signals-fda-drug-market-safety-briefs-4ff61185 -d '<json body>'
```

Example prompt: Pull me a 30-day drug-market safety brief with a scored summary — including recalls, adverse events, and approvals — for the US pharma market overall.

## When to prefer this

Choose this endpoint when you need a pre-aggregated, scored signal (0-100) for pharma safety or market intelligence rather than raw FDA data. It is ideal for research workflows, investment due diligence, or regulatory monitoring that requires a synthesized view across openFDA, BLS, and ClinicalTrials.gov for specific companies (Pfizer, Lilly, J&J) or the broader US drug market. Prefer this over raw ClinicalTrials.gov or openFDA endpoints when you need citations and scoring in one call without building your own aggregation logic.

## Known failure modes

- Invalid or missing 'vertical' enum value returns a validation error
- Unsupported 'entity_id' for non-company verticals may return an error or be ignored
- Upstream FDA or ClinicalTrials.gov data unavailability may result in stale or incomplete scores
- Horizon enum mismatches return a 422 validation error
- Payment failure (insufficient USDC) prevents request from being processed via x402 protocol

## How this service works

Scored drug-market and company safety briefs from openFDA, FDA, BLS and ClinicalTrials.gov: recalls, adverse events, approvals, trial pipelines, shortages, device safety, warning letters and drug prices, for the US market and for Pfizer, Lilly and J&J. Each is a 0-100 score with drivers and citations. POST /v1/brief with {vertical}. Research signal, not medical or investment advice.

## Output

A structured JSON response containing a 0-100 safety or market signal score for the requested pharma vertical or company, along with the key drivers behind the score and citations from source databases (openFDA, FDA, BLS, ClinicalTrials.gov). Coverage includes recalls, adverse events, drug approvals, clinical trial pipelines, drug shortages, device safety signals, FDA warning letters, and drug prices depending on the vertical selected.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "properties": {
  "horizon": {
   "enum": [
    "7d",
    "30d",
    "90d",
    "365d"
   ],
   "type": "string",
   "description": "The window the trend is measured over."
  },
  "vertical": {
   "enum": [
    "drug-market",
    "company-safety",
    "clinical-pipeline",
    "drug-shortages",
    "device-safety",
    "drug-prices",
    "fda-enforcement"
   ],
   "type": "string",
   "description": "Which brief to score."
  },
  "entity_id": {
   "enum": [
    "pfe",
    "lly",
    "jnj"
   ],
   "type": "string",
   "description": "The drug maker, for the company verticals."
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/pocket-network-pharma-signals-fda-drug-market-safety-briefs-4ff61185/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from agent.pocket.network](https://www.zero.xyz/host/agent.pocket.network/llms.txt)