# Polyform Clinical Trials Data API

> Polyform Clinical Trials Data API is a paid API for AI agents from api.polyform.org, paid per call via x402, $0.05/call, status unknown (last checked 2026-10-11).

Returns a paginated list of clinical trials with NCT IDs, phases, statuses, and sponsors via a micropayment-gated GET endpoint

## Facts

- Endpoint: GET https://api.polyform.org/v1/health/clinical-trials?utm_source=zero.xyz
- Price: $0.05/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-11
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/polyform-clinical-trials-data-api-f684c12f
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_RCFxiiOKvUll2CBTj2Eaa

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability polyform-clinical-trials-data-api-f684c12f
```

Example prompt: Can you pull a list of currently recruiting Phase 3 clinical trials and show me their NCT IDs, sponsors, and statuses?

## When to prefer this

Choose this endpoint when you need programmatic access to clinical trial data without registering for an API key or managing credentials — ideal for AI agents that can handle x402 USDC micropayments on Base. Prefer this over direct ClinicalTrials.gov API calls when you want a simple, pay-per-call model with no account setup.

## Known failure modes

- 402 Payment Required if USDC micropayment via x402 is not completed before the request
- Empty results array if no trials match the given query parameters
- Malformed query parameters may return a 400 Bad Request
- Rate limiting or network errors may return 5xx responses
- Stale data if underlying ClinicalTrials.gov data has not been refreshed recently

## How this service works

Pay-per-call data endpoints for AI agents. USDC on Base via x402. No account, no API key — one micropayment per call.

## Output

A JSON object containing a total count of matching clinical trials and an array of trial records, each with an NCT ID (e.g. NCT01234567), trial phase (e.g. PHASE3), recruitment status (e.g. RECRUITING), and sponsor name.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {}
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## Response schema (JSON Schema)

```json
{
 "type": "json",
 "example": {
  "total": 1240,
  "trials": [
   {
    "nctId": "NCT01234567",
    "phase": "PHASE3",
    "status": "RECRUITING",
    "sponsor": "…"
   }
  ]
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/polyform-clinical-trials-data-api-f684c12f/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.polyform.org](https://www.zero.xyz/host/api.polyform.org/llms.txt)