# PubMed Emerging Trends API

> PubMed Emerging Trends API is a paid API for AI agents from pubmed-trends-x402.ben-miles2.workers.dev, paid per call via x402, $0.05/call, status down (last checked 2026-09-14).

Identifies and returns emerging research trends from PubMed biomedical literature

## Facts

- Endpoint: POST https://pubmed-trends-x402.ben-miles2.workers.dev/api/v1/emerging
- Price: $0.05/call
- Payment: x402
- Status: down
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/pubmed-emerging-trends-api-e32e02a3
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_5ig-6K6zfjuw-aVsBRoec

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability pubmed-emerging-trends-api-e32e02a3 -d '<json body>'
```

Example prompt: What are the emerging research trends in CRISPR gene editing from PubMed right now — show me the topics that are gaining the most momentum?

## When to prefer this

Use this endpoint when you need to programmatically discover what biomedical or clinical research topics are currently gaining traction in PubMed, especially for literature review automation, research gap analysis, or competitive intelligence in life sciences. Prefer this over general web search when you need structured, citation-backed trend signals from peer-reviewed literature specifically.

## Known failure modes

- Payment of $0.05 USDC not received — 402 Payment Required response
- Invalid or malformed POST body — 400 Bad Request
- PubMed data source temporarily unavailable — 503 Service Unavailable
- Rate limit exceeded — 429 Too Many Requests
- No emerging trends found for the specified parameters — empty result set

## Output

A list of emerging research trends sourced from PubMed biomedical literature, likely including trending topic names, growth signals or scores, and relevant publication metadata indicating which research areas are gaining momentum.

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/pubmed-emerging-trends-api-e32e02a3/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from pubmed-trends-x402.ben-miles2.workers.dev](https://www.zero.xyz/host/pubmed-trends-x402.ben-miles2.workers.dev/llms.txt)