# PubMed Research Pulse — 7d/30d/90d Publication Volume with Year-over-Year Change

> PubMed Research Pulse — 7d/30d/90d Publication Volume with Year-over-Year Change is a paid API for AI agents from pubmed.sekgen.xyz, paid per call via x402, $0.02/call, status unknown (last checked 2026-09-13).

Returns recent PubMed publication volumes (7-day, 30-day, 90-day windows) with year-over-year change metrics for any biomedical or scientific topic

## Facts

- Endpoint: GET https://pubmed.sekgen.xyz/api/v1/pulse
- Price: $0.02/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-13
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/pubmed-sekgen-xyz-97a4ea65
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_NQKGHZnfdyd2aP072Tayb

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability pubmed-sekgen-xyz-97a4ea65
```

Example prompt: What's the current research pulse for 'checkpoint inhibitor' on PubMed — give me the 7-day, 30-day, and 90-day publication counts and the year-over-year change so I can see if activity is accelerating.

## When to prefer this

Use this endpoint when you need a quick real-time snapshot of how much biomedical research is being published on a specific topic right now, especially when year-over-year momentum or recent acceleration matters. Prefer this over trend or CAGR endpoints when the focus is on recency (days to weeks) rather than long-term historical trajectory. Ideal for drug discovery teams, research analysts, or investment researchers monitoring emerging scientific fields.

## Known failure modes

- Empty or overly broad query returns high noise counts with low signal
- Very niche topic may return zero results for short windows like 7 days
- PubMed indexing lag may cause undercount for very recent publications
- Misspelled medical terms may return zero or misleading counts
- Rate limiting or payment failure returns 402 error

## How this service works

Real-time biomedical research pulse — 7d/30d/90d publication volumes from PubMed with year-over-year change for any medical or scientific topic

## Output

Returns publication counts for the queried biomedical topic across three rolling time windows (7 days, 30 days, 90 days) pulled from PubMed in real time, plus year-over-year percentage change for each window, giving a snapshot of how active and growing the research field currently is.

## Example request

```json
{
 "input": {
  "type": "http",
  "method": "GET",
  "queryParams": {
   "query": "artificial intelligence in medicine"
  }
 }
}
```

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {}
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string"
    },
    "example": {
     "type": "object"
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/pubmed-sekgen-xyz-97a4ea65/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from pubmed.sekgen.xyz](https://www.zero.xyz/host/pubmed.sekgen.xyz/llms.txt)