# Replicate and Batch-Confounding Analyzer

> Replicate and Batch-Confounding Analyzer is a paid API for AI agents from www.mahastrategies.com, paid per call via x402, $0.149001/call, status unknown (last checked 2026-10-21).

Inspects structured sample assignments to detect technical/biological replication issues and batch confounding before comparing experimental groups.

## Facts

- Endpoint: POST https://www.mahastrategies.com/api/v1/compute/biology/replicate-batch-confounding?utm_source=zero.xyz
- Price: $0.149001/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-21
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/replicate-and-batch-confounding-analyzer-6ecdd7df
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_iOT-I-CsZ4Xh2vEJ0T8AX

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability replicate-and-batch-confounding-analyzer-6ecdd7df -d '<json body>'
```

Example prompt: Can you check these 20 synthetic sample assignments for batch confounding and replication issues before I compare my treatment and control groups?

## When to prefer this

Choose this endpoint when you need a pre-analysis sanity check on experimental sample layouts for biological or clinical studies, specifically to detect batch confounding and verify replication structure before downstream statistical comparisons. It is distinct from general statistical testing endpoints because it focuses on study-design validity rather than outcome computation.

## Known failure modes

- Fewer than 1 or more than 128 observations causes a validation error
- Invalid dataClass value (not 'public' or 'synthetic') returns a schema rejection
- Malformed observation objects cause a parsing error
- Insufficient sample size to assess replication returns an underpowered warning
- Service unavailable returns a 5xx error

## How this service works

Inspect structured sample assignments for technical/biological replication and batch confounding before comparing experimental groups. No causal conclusion from labels alone. New modular adapter: retained result recovery for 24 hours, minimal receipt metadata for 90 days. Existing live route unchanged.

## Output

Returns a structured assessment indicating whether the supplied sample assignments exhibit adequate technical and biological replication, flags potential batch confounding between experimental groups, and provides warnings about any confounders detected. No causal conclusions are drawn from labels alone. Results are retained for 24 hours; minimal receipt metadata is retained for 90 days.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "properties": {
  "dataClass": {
   "enum": [
    "public",
    "synthetic"
   ],
   "type": "string"
  },
  "observations": {
   "type": "array",
   "maxItems": 128,
   "minItems": 1
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/replicate-and-batch-confounding-analyzer-6ecdd7df/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from www.mahastrategies.com](https://www.zero.xyz/host/www.mahastrategies.com/llms.txt)