# Saylor Innovations Bioinformatics: Protein Search (UniProt)

> Saylor Innovations Bioinformatics: Protein Search (UniProt) is a paid API for AI agents from saylorinnovations.com, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-01).

Searches UniProtKB for proteins by name, function, or gene and returns key metadata including accession, protein name, gene, organism, sequence length, and Swiss-Prot review status with per-hit detail links.

## Facts

- Endpoint: GET https://saylorinnovations.com/api/bio/protein-search?utm_source=zero.xyz
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-01
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/saylor-innovations-bioinformatics-protein-search-uniprot-cf4a46db
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_girsCoVAuLM-_HBDvWD7F

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability saylor-innovations-bioinformatics-protein-search-uniprot-cf4a46db
```

Example prompt: Can you search UniProtKB for reviewed Swiss-Prot entries for the protein 'BRCA2' and show me the accession numbers, organisms, and sequence lengths?

## When to prefer this

Use this endpoint when you need to quickly retrieve protein metadata (accession, gene, organism, length, review status) from UniProtKB by free-text name, function, or gene query, especially when you want Swiss-Prot reviewed entries by default. Prefer this over direct UniProt API calls when operating in a paid-API workflow (x402) or when you need a simplified, consistent JSON response without handling raw UniProt REST pagination.

## Known failure modes

- Empty results array when no proteins match the query text
- 'found: false' returned for highly specific or misspelled gene/protein names
- Timeout or error if UniProt upstream service is unavailable
- Overly broad queries returning truncated or unranked result sets
- Missing organism filter results in multi-species hits when a single organism was intended

## How this service works

Protein Search (UniProt). Protein search across UniProtKB by name, function or gene: accession, protein name, gene, organism, length and reviewed (Swiss-Prot) status, with a detail link per hit. Reviewed entries by default; ?organism= taxon filter, ?reviewed=false to include TrEMBL.

## Output

A JSON response containing a 'found' boolean and a 'results' array of protein records, each including accession, protein name, gene, organism name, sequence length, reviewed/Swiss-Prot status, and a detail link for further information.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "POST",
      "PUT",
      "PATCH",
      "DELETE",
      "HEAD"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "q": {
       "type": "string",
       "description": "free text: protein name, function, gene (query)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "json"
    },
    "example": {
     "type": "object",
     "required": [
      "found"
     ],
     "properties": {
      "found": {
       "type": "boolean"
      },
      "results": {
       "type": "array",
       "items": {
        "type": "object"
       }
      }
     }
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/saylor-innovations-bioinformatics-protein-search-uniprot-cf4a46db/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from saylorinnovations.com](https://www.zero.xyz/host/saylorinnovations.com/llms.txt)