# Saylor Innovations Bioinformatics – Reactome Pathway Search

> Saylor Innovations Bioinformatics – Reactome Pathway Search is a paid API for AI agents from saylorinnovations.com, paid per call via x402, $0.002/call, status unknown (last checked 2026-10-01).

Search Reactome biological pathways by topic and retrieve pathway ID, name, species, and plain-text summary for matching results

## Facts

- Endpoint: GET https://saylorinnovations.com/api/bio/pathway-search?utm_source=zero.xyz
- Price: $0.002/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-01
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/saylor-innovations-bioinformatics-reactome-pathway-search-c96f12e9
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_SlmfRkHMe45j4NBxb3Qu6

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability saylor-innovations-bioinformatics-reactome-pathway-search-c96f12e9
```

Example prompt: Search Reactome for pathways related to apoptosis and give me the pathway IDs, names, and a plain-text summary for each one found in humans.

## When to prefer this

Use this endpoint when you need to discover or look up biological pathways from the Reactome database by topic keyword, especially when you want human-readable summaries alongside structured identifiers. Prefer this over raw Reactome API calls when you want a simple, pay-per-call interface without managing API keys or complex query syntax. Best suited for bioinformatics agents, research assistants, or pipelines that need to map biological processes to canonical pathway references.

## Known failure modes

- No matching pathways found returns found:false with empty results array
- Ambiguous or overly broad query may return too many loosely related pathways
- Species parameter typo or unsupported species may return no results
- Network or upstream Reactome service unavailability may cause timeout or error response
- Free-text query with highly specific gene names may not match pathway-level descriptions

## How this service works

Pathway Search (Reactome). Search Reactome biological pathways by topic (apoptosis, insulin signaling, DNA repair): pathway id, name, species and a plain-text summary of what the pathway does. Human by default, ?species= for others. Reactome, CC BY 4.0.

## Output

A JSON object with a 'found' boolean and a 'results' array of pathway objects, each containing the pathway ID, name, species, and a plain-text summary describing the biological function of the pathway. Human species is returned by default unless another species is specified.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "POST",
      "PUT",
      "PATCH",
      "DELETE",
      "HEAD"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "q": {
       "type": "string",
       "description": "free text (query)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "json"
    },
    "example": {
     "type": "object",
     "required": [
      "found"
     ],
     "properties": {
      "found": {
       "type": "boolean"
      },
      "results": {
       "type": "array",
       "items": {
        "type": "object"
       }
      }
     }
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/saylor-innovations-bioinformatics-reactome-pathway-search-c96f12e9/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from saylorinnovations.com](https://www.zero.xyz/host/saylorinnovations.com/llms.txt)