# Saylor Innovations Medical Reference – Drug Interaction Check

> Saylor Innovations Medical Reference – Drug Interaction Check is a paid API for AI agents from saylorinnovations.com, paid per call via x402, $0.003/call, status unknown (last checked 2026-10-03).

Checks for drug-drug interactions by querying FDA label text for mentions of co-administered drugs

## Facts

- Endpoint: GET https://saylorinnovations.com/api/medical/interactions?utm_source=zero.xyz
- Price: $0.003/call
- Payment: x402
- Status: unknown
- Last checked: 2026-10-03
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/saylor-innovations-medical-reference-drug-interaction-check-04d50e7c
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_OOeR_QXwBjv-9OBBZmpX4

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability saylor-innovations-medical-reference-drug-interaction-check-04d50e7c
```

Example prompt: Can you check whether warfarin, aspirin, and ibuprofen have any known interactions according to FDA drug label text?

## When to prefer this

Choose this endpoint when you need to surface FDA-sourced, label-text-based drug interaction data for 2–5 drugs simultaneously. It is ideal for clinical decision support, pharmacist tools, or patient safety checks where official regulatory text is required. Prefer this over general drug databases when the source of truth must be the official FDA label rather than curated third-party interaction databases.

## Known failure modes

- Missing or unrecognized drug names may return empty label_mentions with any_mentions set to false
- Fewer than 2 or more than 5 drug names may not be handled correctly
- Misspelled drug names may fail to match FDA database entries
- FDA label data may not cover very new or investigational drugs
- Rate limiting or payment failure may result in HTTP 402 or 429 responses

## How this service works

Drug Interaction Check from FDA Label Text — Health & Medical

## Output

Returns a JSON object containing an array of the queried drugs, a list of label_mentions showing where each drug appears in co-drug FDA label text, and an any_mentions boolean flag indicating whether any interactions were found. Each mention includes relevant excerpts from official FDA labeling.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "POST",
      "PUT",
      "PATCH",
      "DELETE",
      "HEAD"
     ],
     "type": "string"
    },
    "queryParams": {
     "type": "object",
     "properties": {
      "drugs": {
       "type": "string",
       "description": "2-5 comma-separated drug names (query)"
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "json"
    },
    "example": {
     "type": "object",
     "required": [
      "drugs",
      "label_mentions"
     ],
     "properties": {
      "drugs": {
       "type": "array",
       "items": {
        "type": "object"
       }
      },
      "any_mentions": {
       "type": "boolean"
      },
      "label_mentions": {
       "type": "array",
       "items": {
        "type": "object"
       }
      }
     }
    }
   }
  }
 }
}
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/saylor-innovations-medical-reference-drug-interaction-check-04d50e7c/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from saylorinnovations.com](https://www.zero.xyz/host/saylorinnovations.com/llms.txt)