# SCORE2-OP 10-Year CVD Risk Calculator (Age 70–89)

> SCORE2-OP 10-Year CVD Risk Calculator (Age 70–89) is a paid API for AI agents from api.magentlab.com, paid per call via x402, $0.005/call, status unknown (last checked 2026-09-14).

Calculates the ESC 2021 SCORE2-OP 10-year fatal plus non-fatal cardiovascular disease risk percentage for adults aged 70–89 using sex, smoking, diabetes, systolic BP, non-HDL cholesterol, and European geographic risk region.

## Facts

- Endpoint: GET https://api.magentlab.com/api/calc/score2_op
- Price: $0.005/call
- Payment: x402
- Status: unknown
- Last checked: 2026-09-14
- Activations on Zero: 0
- Tags: x402
- Canonical page: https://www.zero.xyz/c/score2-op-10-year-cvd-risk-calculator-age-70-89-9fa90d55
- Structured record (JSON): https://api.zero.xyz/v1/capabilities/cap_-l2GJU_CFM6XVjWbNIQwJ

Status and success rate cover calls made through Zero and Zero's own probes. Third-party monitors may report differently.

## How to call it through Zero

Zero handles the 402 payment challenge and records the run. With the Zero CLI installed (`npm i -g @zeroxyz/cli`):

```sh
zero fetch --capability score2-op-10-year-cvd-risk-calculator-age-70-89-9fa90d55
```

Example prompt: Calculate the SCORE2-OP 10-year cardiovascular risk for a 77-year-old male, current smoker, with diabetes, systolic BP of 155 mmHg, non-HDL cholesterol of 4.2 mmol/L, living in a high-risk European region.

## When to prefer this

Use this endpoint specifically when computing SCORE2-OP risk for patients aged 70–89 per ESC 2021 guidelines using non-HDL cholesterol and European geographic region calibration. Do not use for ages 40–69 (use SCORE2 instead), for patients with diabetes requiring HbA1c/eGFR inputs (use SCORE2-Diabetes), for US populations (use PCE or PREVENT), or when a diagnosis or treatment recommendation is needed.

## Known failure modes

- Age outside 70–89 range returns an error (SCORE2-OP is not for ages 40–69)
- Invalid European risk region string (must be exactly low, moderate, high, or very_high)
- Non-HDL cholesterol outside 1–12 mmol/L range rejected
- Systolic BP outside 50–250 mmHg range rejected
- Missing required query parameters return validation error
- Payment failure (x402) if USDC balance is insufficient

## How this service works

ESC 2021 SCORE2-OP 10-year fatal plus non-fatal CVD percent for age 70-89 from sex, current smoking, diabetes, systolic BP, non-HDL cholesterol, and European geographic risk region (low, moderate, high, very_high). Published sex-specific Table 2 coefficients and region scale1/scale2. Not SCORE2, not SCORE2-Diabetes, not 2013 PCE, not PREVENT, not a diagnosis or statin order. magent does not assay lipids.

## Output

Returns the computed SCORE2-OP 10-year risk percentage for combined fatal and non-fatal cardiovascular events, derived from published ESC 2021 Table 2 sex-specific coefficients and region-specific scale1/scale2 calibration factors.

## Request schema (JSON Schema)

```json
{
 "type": "object",
 "$schema": "https://json-schema.org/draft/2020-12/schema",
 "required": [
  "input"
 ],
 "properties": {
  "input": {
   "type": "object",
   "required": [
    "type",
    "method"
   ],
   "properties": {
    "type": {
     "type": "string",
     "const": "http"
    },
    "method": {
     "enum": [
      "GET",
      "HEAD",
      "DELETE"
     ],
     "type": "string"
    },
    "headers": {
     "type": "object",
     "additionalProperties": {
      "type": "string"
     }
    },
    "queryParams": {
     "type": "object",
     "required": [
      "age",
      "sex",
      "smoker",
      "diabetes",
      "sbp_mm_hg",
      "non_hdl_mmol_l",
      "european_risk_region"
     ],
     "properties": {
      "age": {
       "type": "integer",
       "description": "Age in years (integer 70-89). SCORE2-OP 2021 is for ages 70-89. Not SCORE2 (age 40-69)."
      },
      "sex": {
       "enum": [
        "female",
        "male"
       ],
       "type": "string",
       "description": "Sex used by the sex-specific SCORE2-OP 2021 Table 2 coefficients (female or male)."
      },
      "smoker": {
       "type": "boolean",
       "description": "Current cigarette smoking as assigned by the caller (true or false). magent does not take a smoking history."
      },
      "diabetes": {
       "type": "boolean",
       "description": "History of diabetes as assigned by the caller (true or false). SCORE2-OP includes diabetes. Not SCORE2-Diabetes (no HbA1c, age at diagnosis, or eGFR)."
      },
      "sbp_mm_hg": {
       "type": "number",
       "description": "Systolic blood pressure in mm Hg (50-250). Enters as (SBP-150)/10. magent does not measure blood pressure."
      },
      "non_hdl_mmol_l": {
       "type": "number",
       "description": "Non-HDL cholesterol in mmol/L (1-12). SCORE2-OP charts display non-HDL. The published equation uses TC and HDL at the paper HDL centering 1.4 mmol/L (TC = non-HDL + 1.4). The printed 75-year-old example is non-HDL 4.5 mmol/L. magent does not assay lipids."
      },
      "european_risk_region": {
       "enum": [
        "low",
        "moderate",
        "high",
        "very_high"
       ],
       "type": "string",
       "description": "Geographic SCORE2-OP 2021 calibration region (low, moderate, high, or very_high) as printed in that paper. Not race. Not ethnicity."
      }
     }
    }
   },
   "additionalProperties": false
  },
  "output": {
   "type": "object",
   "required": [
    "type"
   ],

… (truncated)
```

## More

- Live health (JSON, refreshed every minute): https://www.zero.xyz/c/score2-op-10-year-cvd-risk-calculator-age-70-89-9fa90d55/health.json
- [Zero catalog index](https://www.zero.xyz/llms.txt)
- [Other services from api.magentlab.com](https://www.zero.xyz/host/api.magentlab.com/llms.txt)